The Association between Metabolic Syndrome and Its Components and Heart Failure in Patients Referred to a Primary Care Facility

Coelho, Flávio Codeço; Rosa, Maria Luiza Garcia; Moutinho, Marco Aurélio Esposito; Miranda, Verónica A.; Mesquita, Evandro Tinoco

doi:10.1016/j.cardfail.2007.06.651

Cited by 1 publication

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“…We found that metabolic syndrome is very common in current systolic dysfunction HF patients, especially in women and in patients younger than 65 years old. The MetS frequency in our study was similar to the 54% prevalence reported by Coelho, et al 28) In our study, MetS and the mean number of positive MetS parameters were significantly higher in women, as reported in previous studies. 28,29) Increased waist circumference, hypertension, and hypertriglyceridemia were significantly more prevalent among female patients and in a previous study, Levi, et al demonstrated that there was a close relationship between hypertension and heart failure, which are more common in female HF patients.…”

Section: Low Hdl-cholesterol In Heart Failuresupporting

confidence: 92%

“…The MetS frequency in our study was similar to the 54% prevalence reported by Coelho, et al 28) In our study, MetS and the mean number of positive MetS parameters were significantly higher in women, as reported in previous studies. 28,29) Increased waist circumference, hypertension, and hypertriglyceridemia were significantly more prevalent among female patients and in a previous study, Levi, et al demonstrated that there was a close relationship between hypertension and heart failure, which are more common in female HF patients. 20) Although we observed a higher degree of MetS and higher number of parameters in women, mean EF was not different between the males and females so we concluded that there was no association between the number of MetS parameters and EF.…”

Section: Low Hdl-cholesterol In Heart Failuresupporting

confidence: 92%

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Low HDL Levels as the Most Common Metabolic Syndrome Risk Factor in Heart Failure

Karadağ¹,

Akbulut

2009

Int. Heart J.

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Metabolic syndrome (MetS) includes some parameters which are associated with cardiovascular events and risk of developing heart failure (HF). The aim of the present study was to explore the prevalence of metabolic syndrome and individual MetS parameters among heart failure patients. Stable HF patients who had an ejection fraction (EF) < or = 35% were included. They were evaluated for MetS and parameters according to the Adult Treatment Panel III (ATP III) of the National Cholesterol Education Program (NCEP). One hundred and nine patients (72 males, 37 females; mean age, 67 +/- 12 years) were included. The most prevalent parameters were low HDL-C (69%) and hypertension (69%) in all participants. No significant change was observed in the prevalence of these parameters due to gender (P > 0.05). Hypertension, increased waist circumference, and hypertriglyceridemia were all significantly more common in women (P < 0.05). The prevalences of hypo-HDL-emia, hyperglycemia, and hypertension did not differ significantly with an advanced age (P > 0.05), whereas hypertriglyceridemia and high waist circumference were significantly decreased in the elderly (P < 0 05). The overall MetS prevalence was 51% and it was significantly higher in women (76% versus 37%, P : 0.003). The prevalence of MetS clearly decreased with age, although the difference was not statistically significant (61% versus 46%, P : 0.57). The mean number of positive MetS parameters also changed significantly with age (3 +/- 1.4 versus 2.5 +/- 1.3, P : 0.046). EF did not change with mean number of MetS parameters (P > 0.05). Hypo-HDL-emia and similarly hypertension were the 2 most common MetS parameters in HF patients. Hypo-HDL-emia and hypertension were the most common parameters observed in all participants and no significant difference was seen due to gender or age. Even though the prevalence of MetS and the mean number of parameters were significantly more common in females and young patients, EF did not change with changes in these parameters. Based on the results obtained, we conclude that the early diagnosis and treatment of MetS as well as the measurement of individual parameters, especially the most frequent ones, may prevent heart failure or improve its status.

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Section: Low Hdl-cholesterol In Heart Failuresupporting

confidence: 92%