The association between periodontal disease and the risk of myocardial infarction: a pooled analysis of observational studies

Xu, Shuai; Song, Mingbao; Xiong, Yingfei; Xi, Lifeng; He, Yongming; Qin, Zhexue

doi:10.1186/s12872-017-0480-y

Cited by 73 publications

(56 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other proinflammatory states are more common in lower socioeconomic position groups and could play a role in the pathogenesis of kidney disease. For example, periodontal disease is socially patterned and has been consistently linked with cardiovascular disease (38,39), diabetes (40), and systemic autoimmune diseases (41,42). An association with all-cause CKD has also been described, although the relationship between periodontal disease and specific kidney diseases has not been well studied (43).…”

Section: Discussionmentioning

confidence: 99%

Socioeconomic Position and Incidence of Glomerular Diseases

Canney

Induruwage

Sahota

et al. 2020

CJASN

View full text Add to dashboard Cite

Background and objectives Social deprivation is a recognized risk factor for undifferentiated CKD; however, its association with glomerular disease is less well understood. We sought to investigate the relationship between socioeconomic position and the population-level incidence of biopsy-proven glomerular diseases. Design, setting, participants, & measurements In this retrospective cohort study, a provincial kidney pathology database (2000-2012) was used to capture all incident cases of membranous nephropathy (n5392), IgA nephropathy (n5818), FSGS (n5375), ANCA-related GN (ANCA-GN, n5387), and lupus nephritis (n5389) in British Columbia, Canada. Quintiles of area-level household income were used as a proxy for socioeconomic position, accounting for regional differences in living costs. Incidence rates were direct standardized to the provincial population using census data for age and sex and were used to generate standardized rate ratios. For lupus nephritis, age standardization was performed separately in men and women. Results A graded increase in standardized incidence with lower income was observed for lupus nephritis (P,0.001 for trend in both sexes) and ANCA-GN (P50.04 for trend). For example, compared with the highest quintile, the lowest income quintile had a standardized rate ratio of 1.7 (95% confidence interval, 1.19 to 2.42) in women with lupus nephritis and a standardized rate ratio of 1.5 (95% confidence interval, 1.09 to 2.06) in ANCA-GN. The association between income and FSGS was less consistent, in that only the lowest income quintile was associated with a higher incidence of disease (standardized rate ratio, 1.55; 95% confidence interval, 1.13 to 2.13). No significant associations were demonstrated for IgA nephropathy or membranous nephropathy. Conclusions Using population-level data and a centralized pathology database, we observed an inverse association between socioeconomic position and the standardized incidence of lupus nephritis and ANCA-GN.

show abstract

Section: Discussionmentioning

confidence: 99%

Socioeconomic Position and Incidence of Glomerular Diseases

Canney

Induruwage

Sahota

et al. 2020

CJASN

View full text Add to dashboard Cite

show abstract

“…39 A meta-analysis of observational studies including 22 observational studies including 129,630 participants showed that patients with periodontitis have an increased risk of MI (OR 2.02, 95% CI 1.59-2.57). 40 A systematic review to investigate the effects of periodontal therapy in preventing the occurrence of, and management or recurrence of, CVD in patients with chronic periodontitis 41 found very low quality evidence that was insufficient to support or refute whether periodontal therapy can prevent the recurrence of CVD in the long term in patients with chronic periodontitis. No evidence on primary prevention was found.…”

Section: Clinical Conditions Affecting Cardiovascular Riskmentioning

confidence: 99%

Update on cardiovascular prevention in clinical practice: A position paper of the European Association of Preventive Cardiology of the European Society of Cardiology

Piepoli

Abreu

Albus

et al. 2019

Eur J Prev Cardiolog

181

View full text Add to dashboard Cite

European guidelines on cardiovascular prevention in clinical practice were first published in 1994 and have been regularly updated, most recently in 2016, by the Sixth European Joint Task Force. Given the amount of new information that has become available since then, components from the task force and experts from the European Association of Preventive Cardiology of the European Society of Cardiology were invited to provide a summary and critical review of the most important new studies and evidence since the latest guidelines were published. The structure of the document follows that of the previous document and has six parts: Introduction (epidemiology and cost effectiveness); Cardiovascular risk; How to intervene at the population level; How to intervene at the individual level; Disease-specific interventions; and Settings: where to intervene? In fact, in keeping with the guidelines, greater emphasis has been put on a population-based approach and on disease-specific interventions, avoiding re-interpretation of information already and previously considered. Finally, the presence of several gaps in the knowledge is highlighted.

show abstract

“…There is strong evidence that untreated oral diseases and disorders not only negatively affect general health but also increase the probability of diabetes and cardiovascular diseases [4,5]. A meta-analysis of follow-up studies estimated that poor oral health and periodontal diseases may increase the risk of such diseases by approximately 20% [6].…”

Section: Introductionmentioning

confidence: 99%

Oral health status and associated lifestyle behaviors in a sample of Iranian adults: an exploratory household survey

et al. 2020

View full text Add to dashboard Cite

Background: Poor oral hygiene can lead to serious diseases, such as periodontitis, tooth decay, pain and discomfort in teeth or gums, infections, and loss of teeth. In Iran, adults aged 50 y and older are a high-risk group for oral health problems, and this age group will grow in the coming decades. Despite increasing attention on healthy aging, there is relatively less emphasis on oral hygiene and health-related problems. The present study investigated the oral health status of Iranian adults using the oral health self-assessment questionnaire (OHQ) developed by the World Health Organization (WHO). Methods: A population-based household survey of a sample of adults aged 18-65 y was conducted. In this study, the participants were recruited between May and October 2016 in Tabriz, Iran, and the study population was sampled using a multi-stage cluster sampling design. The WHO's OHQ for adults was used for measuring oral health status and oral hygiene behavior. Results: In total, 2310 respondents completed the survey. The mean age (SD) of the participants was 41.6(23.4) y. Males accounted for 48.8% of the participants. Of the 2310 respondents,187 (8.1%) individuals were edentulous, 152(20.7%) of whom were aged 51-65 y. Furthermore, 72.3% of those aged 51-65 y were dentate, and 50% of adults aged 51-65 y said they had 20 or more teeth. About one-third of the participants reported that they did not brush their teeth daily (23% of those aged 18-35 y,35.9% of those aged 36-50 y, and 44.6% for those aged 51-65 y). In the sample, 39.4% of individuals aged 18-35 y,34.1% of individuals aged 36-50 y, and 26.6% of individuals aged 51-65 y had visited a dentist less than 6 month ago. One-third of the participants consumed sweets and sugary drinks daily. Conclusions: Although the majority of Iranian adults considered their oral health status good, only a small percentage of the sample visited their dentist regularly. Furthermore, visits to the dentist declined in accordance with increasing age, a time when the incidence of oral health problems may increase. Poor oral health may increase the risk of adverse health outcomes, particularly among the aging population.

show abstract

The association between periodontal disease and the risk of myocardial infarction: a pooled analysis of observational studies

Cited by 73 publications

References 48 publications

Socioeconomic Position and Incidence of Glomerular Diseases

Socioeconomic Position and Incidence of Glomerular Diseases

Update on cardiovascular prevention in clinical practice: A position paper of the European Association of Preventive Cardiology of the European Society of Cardiology

Oral health status and associated lifestyle behaviors in a sample of Iranian adults: an exploratory household survey

Contact Info

Product

Resources

About