The association between smoking and the development of psoriatic arthritis among psoriasis patients

Abstract

Smoking may be inversely associated with PsA among psoriasis patients. This association is not present among HLA-C*06-positive individuals.

Association between tobacco smoking and response to tumour necrosis factor α inhibitor treatment in psoriatic arthritis: results from the DANBIO registry

“…Smoking is a possible risk factor for developing PsA, but results are conflicting 7 8. However, little is known about the impact of smoking on disease activity and TNFi treatment response in PsA 9–13.…”

Quantifying harmful effects of psoriatic diseases on quality of life: Cardio-metabolic outcomes in psoriatic arthritis study (COMPASS)

“…Although previous studies suggest that psoriasis patients who are smokers (but not those who consume alcohol) may be less likely to develop psoriatic arthritis, we are unaware of other studies that have compared the frequency of smoking and alcohol intake in both these groups of patients [39]. Our findings are important because they demonstrate how prevalent these habits are in patients with psoriatic disease and emphasize the importance of counseling patients about these habits.…”

Early Psoriatic Arthritis

“…28 Evidence for smoking is more conflicting, with at least 2 studies finding smoking a positive risk factor 14,29 and another reporting that smoking is protective. 30 A population-based study using The Health Improvement Network (THIN) database reported a greater incidence rate of psoriatic arthritis in a psoriasis population with increasing body mass index. 31 The severity of psoriasis seems unlikely to be a major risk factor for developing psoriatic arthritis, as most patients with psoriatic arthritis have low Psoriasis Area Severity Index (PASI) scores.…”