The association of arsenic exposure with hypertension and blood pressure: A systematic review and dose–response meta-analysis

Zhao, Jiaxin; Li, Ang; Mei, Yayuan; Zhou, Quan; Li, Yanbing; Li, Kai; Xu, Qun

doi:10.1016/j.envpol.2021.117914

Cited by 39 publications

(24 citation statements)

References 67 publications

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“…Other interacting SNPs were annotated to REN (interacting with Co and As) and AGT (interacting with Co and Zn), which encode renin and angiotensinogen, respectively, with a well-known role on blood pressure regulation. Interestingly, an in vitro study reported that cells exposed to As secreted higher angiotensinogen [ 134 ], which is consistent with the results of a meta-analysis supporting As exposure as a risk factor for hypertension [ 135 ]. Alternatively, some in vitro studies with macrophages [ 136 ] and lung epithelial cells [ 137 ], showed that exposure to Co, the metal mostly interacting with candidate SNPs in our data, increased ROS production, and also increased the DNA damage [ 138 ].…”

Section: Discussionsupporting

confidence: 77%

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

et al. 2022

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Section: Discussionsupporting

confidence: 77%

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

et al. 2022

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“…Similar to our study, a Bangladeshi study with a 13-year follow-up of study subjects aged 4 to 18 years found that drinking-water arsenic exposure led to increased mortality from lung cancer, and cardiovascular and respiratory diseases 34 . In addition, a meta-analysis of 27 studies from 117,769 participants worldwide concluded that arsenic is a potential risk factor for hypertension 35 …”

Section: Discussionsupporting

confidence: 87%

“…34 In addition, a meta-analysis of 27 studies from 117,769 participants worldwide concluded that arsenic is a potential risk factor for hypertension. 35 Smoking is a major public health issue because it increases mortality from cancers, cardiovascular disorders, and respiratory illnesses. The exposure-response association between smoking exposure and all causes of death, including cancer, respiratory disease, and heart disease is amply supported by our study.…”

Section: Discussionmentioning

confidence: 99%

Effect of Arsenic Exposure and Cigarette Smoking on Total and Cause-Specific Mortality

Jia

Li²,

Fan³

et al. 2023

J Occup Environ Med

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The relationship between arsenic exposure and all-cause of death and the combined effects of arsenic exposure and smoking have been poorly evaluated in the available studies. Workers exposed to arsenic had significantly higher mortality rates for all causes (HR = 1.457, 95% CI = 1.242 to 1.708), cancer (HR = 1.517, 95% CI = 1.139 to 2.022), and cerebrovascular disease (HR = 1.796, 95% CI = 1.225 to 2.634). More effective measures should be taken to control arsenic among miners with arsenic exposure.

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“…We classified studies with scores >7 stars as “high quality”; otherwise, the study was classified as “low quality.” The Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies was used to evaluate the quality of cross-sectional studies ( 23 ). This tool consists of 14 questions, but only seven questions applicable to cross-sectional studies were used ( 24 ). Studies were rated as poor, fair, or good; if the study did not adjust for any variables, it was rated as poor.…”

Section: Methodsmentioning

confidence: 99%

Association between exposure to greenness and atopic march in children and adults—A systematic review and meta-analysis

Wang

Zhou²,

Zhi³

2023

Front. Public Health

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IntroductionAllergic diseases are a global public health problem. Food allergy, atopic dermatitis (AD), allergic rhinoconjunctivitis, allergic rhinitis (AR) and asthma represent the natural course of allergic diseases, also known as the “atopic march”. In recent years, a large number of studies have been published on the association between greenness exposure and allergic diseases. However, systematic reviews on the association between greenness exposure and multiple allergic diseases or atopic march are lacking.MethodsIn this study, PubMed, EMBASE, ISI Web of Science, and Scopus were systematically searched. Meta-analyses were performed if at least three studies reported risk estimates for the same outcome and exposure measures.ResultsOf 2355 records, 48 studies were included for qualitative review. Five birth cohort studies, five cross-sectional studies, and one case-control study were included for asthma meta-analysis, respectively. Four birth cohort studies were included for AR meta-analysis. Our results support that exposure to a greener environment at birth reduces the risk of asthma and AR in childhood. In addition, higher greenness exposure was associated with decreased odds of current asthma in children.DiscussionThere was a large heterogeneity among the included studies and most of them did not specify the vegetation type and causative allergens. Therefore the study results need to be further validated. In addition, a small number of studies evaluated the association between greenness and food allergy, AD and allergic rhinoconjunctivitis. More research is needed to strengthen our understanding of the association between greenness and allergic diseases.

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The association of arsenic exposure with hypertension and blood pressure: A systematic review and dose–response meta-analysis

Cited by 39 publications

References 67 publications

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

Effect of Arsenic Exposure and Cigarette Smoking on Total and Cause-Specific Mortality

Association between exposure to greenness and atopic march in children and adults—A systematic review and meta-analysis

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