The association of body mass index values with severity and phenotype of sleep-disordered breathing

Özdilekcan, Çiğdem; Özdemir, Tarkan; Türkkanı, Mustafa Hamidullah; Sur, Halil Yılmaz; Katoue, Maram Gamal

doi:10.5578/tt.69057

Cited by 7 publications

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“…Despite the strong association between OSAS and obesity, studies have shown that an important number of OSAS patients have a BMI within the normal range [ 23 ]. However, this relationship is reinforced by studies concluding that patients with a higher BMI experience frequent ODI periods, resulting in a higher AI and decreased sleep efficiency [ 24 ]. Moreover, a 10% increase in weight gain was associated with a huge probability of developing OSAS, and a 10% weight loss predicted a 26% decrease in AHI [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

et al. 2022

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Background: Obstructive sleep apnea syndrome (OSAS) is a significant public health issue. In the general population, the prevalence varies from 10% to 50%. We aimed to phenotype comorbidities in OSAS patients referred to the primary health care (PHC) system. Methods: We enrolled 1496 patients referred to the PHC system for any respiratory- or sleep-related issue from November 2015 to September 2017. Some patients underwent polysomnography (PSG) evaluation in order to establish OSAS diagnosis. The final study population comprised 136 patients, and the Charlson comorbidity index was assessed. Categorical principal component analysis and TwoStep clustering was used to identify distinct clusters in the study population. Results: The analysis revealed three clusters: the first with moderate OSAS, obesity and a high ESS score without significant comorbidities; the second with severe OSAS, severe obesity with comorbidities and the highest ESS score; and the third with severe OSAS and obesity without comorbidities but with a high ESS score. The clusters differed in age (p < 0.005), apnea–hypopnea index, oxygen desaturation index, arousal index and respiratory and desaturation arousal index (p < 0.001). Conclusions: Predictive comorbidity models may aid the early diagnosis of patients at risk in the context of PHC and pave the way for personalized treatment.

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Section: Discussionmentioning

confidence: 99%

Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

et al. 2022

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“…Obstructive sleep apnea (OSA) is a common breathing disorder characterized by repetitive episodes of upper airway obstruction and is positively associated with body mass index and age (Zhang, 2012). Of the adult population, up to 50% have OSA, whereas 23.4% of women and 49.7% of men are suffering from moderate to severe OSA (Heinzer et al, 2015; Özdilekcan, Özdemir, Türkkanı, Sur, & Katoue, 2019). The Apnea–Hypopnea Index is a main metric measured by polysomnography for diagnosing OSA, reflecting the average number of significant breathing disturbances per hour of sleep (Zhang, 2012).…”

Section: Introductionmentioning

confidence: 99%

A Meta-Analysis of Sleep Disorders and Nonalcoholic Fatty Liver Disease

Lin

Chen

et al. 2022

Gastroenterology Nursing

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Nonalcoholic fatty liver disease is a type of metabolic disease, and recent research indicates that it may be associated with sleep disorders. We conducted a meta-analysis of current studies to estimate the associations between nonalcoholic fatty liver disease and sleep situation, including sleep duration, daytime sleepiness, and sleep disorder. This study follows the checklist of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). Articles in the recent 10 years were searched from five databases. Eighteen articles, which met the eligibility criteria, were included in this meta-analysis. The results show that patients with nonalcoholic fatty liver disease have a shorter sleep duration and higher Epworth Sleepiness Scale score. Patients with short sleep duration (≤6 hours per night) or with obstructive sleep apnea have a higher risk of nonalcoholic fatty liver disease. In conclusion, there is a significant association between nonalcoholic fatty liver disease and sleep disorders in the included studies. In addition, patients with nonalcoholic fatty liver disease may have more severe daytime sleepiness and shorter sleep duration. More attention should be paid to the sleep situation of nonalcoholic fatty liver disease patients to potentially slow the disease progression.

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Adaptation and validation of the Chinese version of the Sleep Quality Questionnaire

et al. 2022

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The association of body mass index values with severity and phenotype of sleep-disordered breathing

Cited by 7 publications

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Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

A Meta-Analysis of Sleep Disorders and Nonalcoholic Fatty Liver Disease

Adaptation and validation of the Chinese version of the Sleep Quality Questionnaire

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