2020
DOI: 10.1016/j.obmed.2020.100262
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The association of body mass index and quantitative 24-h urine metabolites in patients with nephrolithiasis: A systematic review and dose-response meta-analysis

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“…Moreover, it was indicated a linear dose–response association between BMI and the 24 h excretion of oxalate, uric acid, sodium, phosphate, citrate, and creatinine, indicating that as BMI increases, so does the excretion of these substances. Individuals with excess weight are at a higher risk of forming kidney stones, as they excrete more stone-promoting substances (calcium, sodium, oxalate, and uric acid) as well as stone inhibitors (citrate and magnesium), even though the urinary pH and prevalence of kidney stones remain higher in these groups [ 106 ]. The higher urinary excretion of stone-forming substances in obese patients is probably due to a combination of factors.…”
Section: Disease Influenced By Lifestyle Related To Kidney Stone Diseasementioning
confidence: 99%
“…Moreover, it was indicated a linear dose–response association between BMI and the 24 h excretion of oxalate, uric acid, sodium, phosphate, citrate, and creatinine, indicating that as BMI increases, so does the excretion of these substances. Individuals with excess weight are at a higher risk of forming kidney stones, as they excrete more stone-promoting substances (calcium, sodium, oxalate, and uric acid) as well as stone inhibitors (citrate and magnesium), even though the urinary pH and prevalence of kidney stones remain higher in these groups [ 106 ]. The higher urinary excretion of stone-forming substances in obese patients is probably due to a combination of factors.…”
Section: Disease Influenced By Lifestyle Related To Kidney Stone Diseasementioning
confidence: 99%