The association of choroidal thickness with rheumatoid factor and anti-cyclic citrullinated peptide in rheumatoid arthritis

Yener, Arif Ülkü; Şahin, Kubilay

doi:10.1007/s10792-019-01265-8

Cited by 5 publications

(2 citation statements)

References 29 publications

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“…Two published studies reported that RA patients had a thinner CT than healthy controls. [ 12 , 13 ] The reason for this may be related to matrix-metalloproteinase (MMP)-2 and MMP-9, which are found to be higher in RA-associated ILD (RA-ILD) patients compared to RA without ILD (RA-noILD) patients and are effective on vascular structures as well. [ 14 , 15 ] Moreover, TNF-α, VEGF, and PDGF play a crucial function in the pathogenesis and pathophysiology of ocular involvement and ILD.…”

Section: Introductionmentioning

confidence: 99%

Association between choroidal thickness and interstitial lung disease in patients with rheumatoid arthritis: A cross-sectional study

Kaymaz,

Savurmuş,

Karasu

et al. 2023

Arch Rheumatol

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Objectives: This study aimed to evaluate choroidal thickness (CT) in patients with rheumatoid arthritis (RA) and healthy controls and to determine its relationship with RA-associated interstitial lung disease (RA-ILD). Patients and methods: A total of 63 patients with RA and 36 age- and sex-matched healthy controls were recruited in the cross-sectional study. Serological findings, Disease Activity Score-28, disease duration, and medical treatment of patients were recorded. Patients with RA were subdivided into two groups: patients with RA-ILD (Group 1) and patients with RA but without ILD (RA-noILD; Group 2). CTs were measured using enhanced depth imaging optical coherence tomography. CT was measured at five points: the subfoveal region, 750 μm nasal and temporal to the fovea, 1500 μm nasal and temporal to the fovea. Patients with RA-ILD were evaluated with delta high-resolution computed tomography (ΔHRCT) and pulmonary function test to determine the severity of interstitial lung disease. Results: Four of 63 RA patients were excluded due to comorbidities. Thus, 59 RA patients, 20 in the RA-ILD group and 39 in the RA-noILD group, were included in the analyses. The RA groups were similar in terms of clinical characteristics and laboratory findings. There were statistically significant differences between Group 1, Group 2 and healthy controls (Group 3) compared to all CT values (p<0.05). The mean CT measured at 750 μm and 1500 μm nasal to the fovea was lowest in the RA-ILD group, followed by the RA-noILD and healthy groups (p<0.05). CT measurements did not correlate with the pulmonary function test and ΔHRCT. Conclusion: RA-ILD patients had a thinner CT measured at nasal points. However, there was no association between CT measurements and the severity of ILD.

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Section: Introductionmentioning

confidence: 99%

Association between choroidal thickness and interstitial lung disease in patients with rheumatoid arthritis: A cross-sectional study

Kaymaz,

Savurmuş,

Karasu

et al. 2023

Arch Rheumatol

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“…2 El factor reumatoide (FR) es un autoanticuerpo en contra de la porción de fragmento cristalizable (Fc) de la IgG y se encuentra en un 70-80% de los casos con AR correlacionándose con mayor enfermedad articular, así como con manifestaciones extraarticulares; a su vez, la presencia de autoanticuerpos antipéptido cíclico citrulinado (anti-PCC) tiene un alto valor predictivo para la progresión radiográfica y desarrollo de AR erosiva, así como de la presencia de manifestaciones extraarticulares. 3,4 Se sabe que estos autoanticuerpos anti-PCC pueden aparecer hasta 10 años previos a los datos clínicos articulares en casos con AR. 5,6 Éstos pueden unirse a residuos proteicos citrulinados de diversas proteínas propias (colágena tipo II, histonas, fibronectina, fibrinógeno, vimentina y enolasas).…”

Section: Introductionunclassified

Escleritis y anticuerpos antipéptido cíclico citrulinado como presentación inicial de artritis reumatoide

Concha-del-Río¹,

Cheja-Kalb²,

Prado-Larrea³

et al. 2020

Anales Médicos De La Asociación Médica Del Centro Médico ABC

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Choroidal thickness in eyes of rheumatoid arthritis patients measured using optical coherence tomography: A systematic review and meta-analysis

Fekrazad,

Shahrabi Farahani,

Salehi

et al. 2024

Survey of Ophthalmology

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The association of choroidal thickness with rheumatoid factor and anti-cyclic citrullinated peptide in rheumatoid arthritis

Cited by 5 publications

References 29 publications

Association between choroidal thickness and interstitial lung disease in patients with rheumatoid arthritis: A cross-sectional study

Association between choroidal thickness and interstitial lung disease in patients with rheumatoid arthritis: A cross-sectional study

Escleritis y anticuerpos antipéptido cíclico citrulinado como presentación inicial de artritis reumatoide

Choroidal thickness in eyes of rheumatoid arthritis patients measured using optical coherence tomography: A systematic review and meta-analysis

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