The association of gonorrhoea and syphilis with premature birth and low birthweight.

Donders, Gilbert; Desmyter, Jan; Wet, D. H. De; Assche, F.A. Van

doi:10.1136/sti.69.2.98

Cited by 75 publications

(64 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In South Africa, for example, gonorrhoea has been associated with preterm delivery. Syphilis treatment may be omitted and significantly increases the risk of both preterm birth and stillbirth [41,42]. However, there is a problem of cause-and-effect in analysing these variables as mothers who had preterm deliveries will also have a shorter time in which to accumulate antenatal visits.…”

Section: Discussionmentioning

confidence: 99%

Adverse birth outcomes in a malarious area

et al. 2005

View full text Add to dashboard Cite

SUMMARYTo determine factors associated with fetal growth, preterm delivery and stillbirth in an area of high malaria transmission in Southern Malawi, a cross-sectional study of pregnant women attending and delivering at two study hospitals was undertaken. A total of 243 (17 . 3 %) babies were preterm and 54 (3 . 7%) stillborn. Intra-uterine growth retardation (IUGR) occurred in 285 (20 . 3 %), of whom 109 (38 . 2%) were low birthweight and 26 (9 . 1%) preterm. Factors associated with IUGR were maternal short stature [adjusted odds ratio (AOR) 1 . 6, 95 % confidence interval (CI) 1 . 0-2 . 5] ; primigravidae (AOR 1 . 9, 95 % CI 1 . 4-2 . 7) ; placental or peripheral malaria at delivery (AOR 1 . 4, 95 % CI 1 . 0-1 . 9) and maternal anaemia at recruitment (Hb <8 g/dl) (AOR 1 . 9, 95% CI 1 . 3-2 . 7). Increasing parasite density in the placenta was associated with both IUGR (P=0 . 008) and prematurity (P=0 . 02). Factors associated with disproportionate fetal growth were maternal malnutrition [mid-upper arm circumference (MUAC) <23 cm, AOR 1 . 9, 95% CI 1 . 0-3 . 7] and primigravidae (AOR 1 . 8, 95% CI 1 . 0-3 . 1). Preterm delivery and stillbirth were associated with <5 antenatal care visits (AOR 2 . 2, 95% CI 1 . 3-3 . 7 and AOR 3 . 1, 95 % CI 1 . 4-7 . 0 respectively) and stillbirth with a positive Venereal Disease Research Laboratory (VDRL) test (AOR 4 . 7, 95 % CI 1 . 5-14 . 8). Interventions to reduce poor pregnancy outcomes must reduce the burden of malaria in pregnancy, improve antenatal care and maternal malnutrition.

show abstract

Section: Discussionmentioning

confidence: 99%

Adverse birth outcomes in a malarious area

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Many agents are associated with fetal growth disorders, including toxoplasma, rubella, cytomegalovirus and herpes simplex. In addition, different studies conclude that there is an association between LBW and such maternal infections as Chlamydia, β-hemolytic Streptococcus, Ureaplasma urealyticum, Mycoplasma, Trichomonas, Staphylococcus aureus and other vaginal infections, as well as untreated gonorrhea and syphilis 25 . A study by Dasanayake 26 concludes that periodontal disease during pregnancy is a potential risk factor for LBW.…”

Section: Infectionsmentioning

confidence: 99%

Risk Factors of Low Birth Weight Baby: A Review

Begum

Hassan²,

Saha³

et al. 2017

Faridpur Med Coll J

View full text Add to dashboard Cite

Abstract:Low birth weight (LBW) is one of the main predictors of infant mortality. The global incidence of LBW is around 17%, although estimates vary from 19% in the developing countries like Bangladesh to 5-7% in the developed countries. About one third of delivery is low birth weight. LBW is generally associated with situations in which uterine malnutrition is produced due to alterations in placental circulation. There are many known risk factors, the most important of which are socio-economic factors, medical risks before or during gestation and maternal lifestyles. However, although interventions exist to prevent many of these factors before and during pregnancy, the incidence of LBW has not decreased.

show abstract

“…6,7 Other RTIs associated with adverse birth outcomes include bacterial vaginosis (BV), gonors s rhoea, and Chlamydia trachomatis and Trichomonas vaginalis infections. [8][9][10][11][12] A few studies have documented other maternal factors associated with adverse pregnancy outcomes in subs Saharan Africa. [13][14][15][16][17][18][19][20] However, there are few data on the examination of multiple determinants of birth outcome and the proportion of adverse birth events ats s tributable to these factors from the study region, partly because of a lack of simple, inexpensive diagnostic methods.…”

Section: Introductionmentioning

confidence: 99%

Adverse birth outcomes in United Republic of Tanzania - impact and prevention of maternal risk factors

Watson-Jones

Weiss

Changalucha

et al. 2007

Bull World Health Organ

130

121

View full text Add to dashboard Cite

Objective To determine risk factors for poor birth outcome and their population attributable fractions. Methods 1688 women who attended for antenatal care were recruited into a prospective study of the effectiveness of syphilis screening and treatment. All women were screened and treated for syphilis and other reproductive tract infections (RTIs) during pregnancy and followed to delivery to measure the incidence of stillbirth, intrauterine growth retardation (IUGR), low birth weight (LBW) and preterm live birth. Findings At delivery, 2.7% of 1536 women experienced a stillbirth, 12% of live births were preterm and 8% were LBW. Stillbirth was independently associated with a past history of stillbirth, short maternal stature and anaemia. LBW was associated with short maternal stature, ethnicity, occupation, gravidity and maternal malaria whereas preterm birth was associated with occupation, age of sexual debut, untreated bacterial vaginosis and maternal malaria. IUGR was associated with gravidity, maternal malaria, short stature, and delivering a female infant. In the women who had been screened and treated for syphilis, in between 20 and 34% of women with each outcome was estimated to be attributable to malaria, and 63% of stillbirths were estimated as being attributable to maternal anaemia. Screening and treatment of RTIs was effective and no association was seen between treated RTIs and adverse pregnancy outcomes. Conclusion Maternal malaria and anaemia continue to be significant causes of adverse pregnancy outcome in sub-Saharan Africa. Providing reproductive health services that include treatment of RTIs and prevention of malaria and maternal anaemia to reduce adverse birth outcomes remains a priority. Voir page 16 le résumé en français. En la página 16 figura un resumen en español.

show abstract

The association of gonorrhoea and syphilis with premature birth and low birthweight.

Cited by 75 publications

References 19 publications

Adverse birth outcomes in a malarious area

Adverse birth outcomes in a malarious area

Risk Factors of Low Birth Weight Baby: A Review

Adverse birth outcomes in United Republic of Tanzania - impact and prevention of maternal risk factors

Contact Info

Product

Resources

About