2023
DOI: 10.3390/jpm13060968
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The Association of IFN-γ, TNF-α, and Interleukins in Bronchoalveolar Lavage Fluid with Lung Cancer: A Prospective Analysis

Abstract: Lung cancer is a leading cause of cancer-related mortality worldwide. Identifying novel diagnostic and prognostic biomarkers is essential for improving patient outcomes. This study aimed to investigate the predictive role of cytokines from bronchoalveolar lavage fluid (BALF) in lung cancer diagnosis and prognosis. A prospective study was conducted on 33 patients with suspected lung cancer, divided into inflammatory and non-inflammatory BALF groups. Inflammatory markers in BALF were assessed, and their associat… Show more

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Cited by 2 publications
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“…In case of lungs, inflammation has been shown to be a major factor affecting the tissue architecture and ultimately organ physiology. [ 18 ] In view of this, the present study was conducted to evaluate the safety aspects of the combination with the aforementioned endpoints. TNF-α is a potent systemic pro-inflammatory cytokine, principally generated by activated macrophages, and is essential for the pathophysiology of lung disease.…”
Section: Discussionmentioning
confidence: 99%
“…In case of lungs, inflammation has been shown to be a major factor affecting the tissue architecture and ultimately organ physiology. [ 18 ] In view of this, the present study was conducted to evaluate the safety aspects of the combination with the aforementioned endpoints. TNF-α is a potent systemic pro-inflammatory cytokine, principally generated by activated macrophages, and is essential for the pathophysiology of lung disease.…”
Section: Discussionmentioning
confidence: 99%