The association of plasma prorenin level with an oxidative stress marker, 8-OHdG, in nondiabetic hemodialysis patients

Abstract

The plasma prorenin level and (P)RR expression level in PBMCs increased, and the plasma prorenin level was associated with plasma 8-OHdG level independent of circulating RAS in non-DM-HD patients.

Assessment of left ventricular function by three‐dimensional speckle‐tracking echocardiography in well‐treated type 2 diabetes patients with or without hypertension

“…This indicates that blood glucose level and preload have important impacts on LV systolic function, which is in accordance with previous studies . Hyperglycemia can damage myocardial systolic function in a variety of ways, including oxidative stress, overactivation of the renin‐angiotensin system, or protein kinase C . Systolic strain is remarkably load‐dependent and becomes significantly higher or lower as volume loading increases or decreases, respectively .…”

Association of 8-hydroxy-2’-deoxyguanosine with various demographic and biochemical parameter in a group of hemodialysis patients

“…In contrast to our finding, Morishita et al showed that plasma prorenin levels was associated with plasma 8-OHdG level. Plasma prorenin may contribute to increased oxidative stress in non-diabetes mellitus-HD patients (27).…”

Aplysin Protects Against Alcohol‐Induced Liver Injury Via Alleviating Oxidative Damage and Modulating Endogenous Apoptosis‐Related Genes Expression in Rats

“…8‐OHdG is a sensitive and specific marker of oxidative damage to DNA (Morishita et al., ). Our result showed that Aplysin decreased the plasma levels of 8‐OHdG as compared with that in the alcohol‐treated group, suggesting that Aplysin could prevent alcohol‐induced DNA damage.…”