The Autonomic Symptom Profile

Suárez, Guillermo A.; Opfer‐Gehrking, Tonette L.; Offord, Kenneth P.; Atkinson, E. J.; O’Brien, Peter C.; Low, Phillip A.

doi:10.1212/wnl.52.3.523

Cited by 283 publications

(258 citation statements)

References 14 publications

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“…Headache patients also filled in headache diaries for the same period. Every subject answered several questionnaires including: Epworth Sleepiness Scale (13), questions adapted from Karolinska Sleep Questionnaire (14), Pittsburgh Sleep Quality Index (PSQI) (15), Hospital Anxiety and Depression Subscales (16), and 10 questions from the Autonomic Symptom Profile (17,18). As a supplement to the Epworth (4)).…”

Section: Methodsmentioning

confidence: 99%

Sleep quality and arousal in migraine and tension-type headache: the headache-sleep study

et al. 2014

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Objectives -The present paper summarizes and compares data from our studies on subjective and objective sleep quality and pain thresholds in tension-type headache (TTH), migraine, and controls. Material and methods -In a blinded controlled explorative study, we recorded polysomnography (PSG) and pressure, heat, and cold pain thresholds in 34 controls, 20 TTH, and 53 migraine patients. Sleep quality was assessed by questionnaires, sleep diaries, and PSG. Migraineurs who had their recordings more than 2 days from an attack were classified as interictal while the rest were classified as either preictal or postictal. Interictal migraineurs (n = 33) were also divided into two groups if their headache onsets mainly were during sleep and awakening (sleep migraine, SM), or during daytime and no regular onset pattern (non-sleep migraine, NSM). TTH patients were divided into a chronic or episodic group according to headache days per month. Results -Compared to controls, all headache groups reported more anxiety and sleep-related symptoms. TTH and NSM patients reported more daytime tiredness and tended to have lower pain thresholds. Despite normal sleep times in diary, TTH and NSM had increased slow-wave sleep as seen after sleep deprivation. Migraineurs in the preictal phase had shorter latency to sleep onset than controls. Except for a slight but significantly increased awakening index SM, patients differed little from controls in objective measurements. Conclusions -We hypothesize that TTH and NSM patients on the average need more sleep than healthy controls. SM patients seem more susceptible to sleep disturbances. Inadequate rest might be an attack-precipitating-and hyperalgesia-inducing factor.

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Section: Methodsmentioning

confidence: 99%

Sleep quality and arousal in migraine and tension-type headache: the headache-sleep study

et al. 2014

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“…The patient should be asked about these symptoms when a medical history is taken in the office, although the correlation of symptoms with overall autonomic deficits is weak (149,171). However, these symptoms may occur quite late in the disease course (25,27,147,149).…”

Section: Screening and Diagnosismentioning

confidence: 99%

Diabetic Neuropathy: A Position Statement by the American Diabetes Association

et al. 2016

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“…34 Questions with a yes/no response format were used for the orthostatic domain (''In the past month, have you ever felt faint, dizzy, or 'goofy,' or had difficulty thinking 1) soon after eating a meal, 2) soon after standing up from a sitting or lying down position, or 3) during or soon after being in a hot bath, hot shower, hot tub, or sauna? ''), the secretomotor (including sudomotor symptoms) and vasomotor domains (''In the past month, have you ever noticed color changes in your skin [hands, feet, or other body parts], such as red, white, or purple?…”

Section: Autonomic Dysfunctionmentioning

confidence: 99%

The impact of hypogonadism and autonomic dysfunction on fatigue, emotional function, and sexual desire in male patients with advanced cancer

Strasser

Palmer

Schover

et al. 2006

Cancer

108

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BACKGROUND.The objective of this study was to determine whether hypogonadism and autonomic dysfunction contribute substantially to cancer‐related fatigue, decreased sexual desire, and depression in male patients with advanced, incurable cancer.METHODS.Forty‐eight patients who had received no major antineoplastic intervention for at least 2 weeks were tested for autonomic dysfunction by using Ewing tests. Total and free testosterone levels were measured. Multivariate analyses were performed to test the relation of these factors with the Functional Assessment of Cancer Therapy (FACT) (the Functional Assessment of Anorexia/Cachexia Therapy [FAACT] scale and the Functional Assessment of Chronic Illness Therapy‐Fatigue [FACIT‐F] subscale), the Hospital Anxiety and Depression Scale (HADS), the Edmonton Symptom Assessment Scale, the Sexual Desire Inventory, and sexual function (Cancer Rehabilitation Evaluation System subscale). Common causes for fatigue (anemia, depression, malnutrition, symptom distress, and medications) also were considered.RESULTS.Thirty‐eight of 47 patients (81%) had autonomic dysfunction, although it was not associated significantly with the other variables examined. Twenty‐nine of 45 patients (64%) had a low level of free testosterone (hypogonadism), which was correlated with the HADS Anxiety score (P = .002), the FACT Emotional Well‐Being score (P = .02), and the HADS Depression score (P = .04). Hypogonadal men also had lower scores on the FACT Functional Well‐Being scale (P = .01) and the FACIT‐F subscale (P = .05). Men who reported symptoms related to weight loss (FAACT scale) had significantly lower levels of free testosterone (r = 0.34; P = .02) but did not differ from the other group in actual weight loss (P = .22). The total testosterone level was not appropriate for screening of hypogonadism unless the patients had values <100 ng/ mL. Logistic regression analysis failed to reveal a distinct multivariate model of autonomic dysfunction or hypogonadism that predicted clinical outcomes.CONCLUSIONS.Hypogonadism is a frequent condition in patients with advanced, incurable cancer and is associated with negative mood, fatigue, and symptoms related to anorexia/cachexia. Cancer 2006. © 2006 American Cancer Society.

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The Autonomic Symptom Profile

Abstract: We describe a questionnaire that measures autonomic symptoms and present evidence for its validity. The instrument shows promise in assessing autonomic symptoms in clinical trials and epidemiologic studies.

Cited by 283 publications

References 14 publications

Sleep quality and arousal in migraine and tension-type headache: the headache-sleep study

Sleep quality and arousal in migraine and tension-type headache: the headache-sleep study

Diabetic Neuropathy: A Position Statement by the American Diabetes Association

The impact of hypogonadism and autonomic dysfunction on fatigue, emotional function, and sexual desire in male patients with advanced cancer

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