The avian subpallium: New insights into structural and functional subdivisions occupying the lateral subpallial wall and their embryological origins

Kuenzel, Wayne J.; Medina, Loreta; Csillag, András; Perkel, David J.; Reiner, Anton

doi:10.1016/j.brainres.2011.09.037

Cited by 83 publications

(115 citation statements)

References 351 publications

(832 reference statements)

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“…This effect is not due to general memory impairments, as no deficits are observed in tests of nonsocial memory [40]. Because the medial amygdala in birds (formerly nucleus taeniae [43,44]) exhibits at least a modest level of OTA binding [34], the amygdala could be another site of action that by itself, or together with the LS, mediates the effects of OTA observed here.…”

Section: Discussionmentioning

confidence: 88%

Oxytocin-like receptors mediate pair bonding in a socially monogamous songbird

Klatt

Goodson

2013

Proc. R. Soc. B.

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Although many species form socially monogamous pair bonds, relevant neural mechanisms have been described for only a single species, the prairie vole (Microtus ochrogaster). In this species, pair bonding is strongly dependent upon the nonapeptides oxytocin (OT) and vasopressin, in females and males, respectively. Because monogamy has evolved many times in multiple lineages, data from additional species are required to determine whether similar peptide mechanisms modulate bonding when monogamy evolves independently. Here we test the hypothesis that OT-like receptor activation is required for pair bond formation in the socially monogamous zebra finch (Taeniopygia guttata). Males and females were administered chronic intracerebroventricular infusions of saline or an OT receptor antagonist and were observed twice daily for 3 days in a colony environment. A variety of affiliative, aggressive and other behaviours were quantified. The antagonist produced significant and selective effects on pair bonding (latency to pair; number of sessions paired; stable pairing) and the associated behaviour of allopreening. Importantly, findings for males follow the trends of females; this yields main effects of treatment in two-way ANOVAs, although within-sex analyses are significant only for females. These data provide evidence for both convergent evolution and species diversity in the neuroendocrine mechanisms of pair bonding.

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Section: Discussionmentioning

confidence: 88%

Oxytocin-like receptors mediate pair bonding in a socially monogamous songbird

Klatt

Goodson

2013

Proc. R. Soc. B.

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Section: Nih-pa Author Manuscriptmentioning

confidence: 99%

“…We do not yet have an immediate early gene that is activated in pallidal cells to determine if it too forms topographically organized columns with the striatum and pallium. The pallidal cells intermingled in the anterior striatum of birds (Kuenzel et al, 2011) presumably make up the pallidal component of the somatic motor and vocal motor columns. We do not know if there are striatal, pallidal, and arcopallial components to the dorsal pallial columns.…”

Section: Functional Column Organization Of the Avian Cerebrummentioning

confidence: 99%

“…A third, but less acknowledged, hypothesis is that the different subdivisions of the anterior DVR as a field are homologous to both cortical and claustrum/amygdala cell types Molnar and Butler, 2002). To address these hypotheses, a number of elegant comparative and manipulation experiments have since been performed, but still with continued conflicting conclusions Medina and Abellan, 2009;Nomura et al, 2009;Uchida et al, 2010;Wang et al, 2010; Aboitiz, 2011;Butler et al, 2011;Kuenzel et al, 2011;Medina et al, 2011;Puelles, 2011;Tanaka et al, 2011;Atoji and Karim 2012;Dugas-Ford et al, 2012;Suzuki et al, 2012).Resolving these hypotheses, we believe, is in part hampered by yet another set of unanswered questions on our still limited understanding of overall avian brain organization.To address this issue, here we quantitatively analyzed telencephalic expression profiles of 46 constitutive and 6 activity-responsive genes (52 total; (Kubikova et al, 2010), the SEMA6A axon guidance receptor , cannabinoid receptor (Soderstrom et al, 2004), and retinoic acid orphan related receptor beta (ROR-β; this study); the NRN, BDNF, and SCUBE1 protein ligands (Wada et al, 2006;Lovell et al, 2008); the DLX6 (this study), FOXP1, FOXP2, ER81, COUP-TF2, LHX8, LHX9, NKX2.1, PAX6, EGR1, C-FOS, and C-JUN transcriptions factors (Jarvis and Nottebohm, 1997;Kimpo and Doupe, 1997;Haesler et al, 2004;Jarvis et al, 2005;Abellan et al, 2009); the FKBP1A (this study), DUSP1 (a.k.a. map kinase phosphatase 1 [mkp1]), and PPAPDC1A enzymes Horita et al, 2010Horita et al, , 2012; and a diverse set of membrane and cytoplasmic genes, including ARPP16 (this study), TMEM100 (this study), ARC, CADPS2, and S100B (Wada et al, 2006;Lovell et al, 2008) (Table 1).…”

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confidence: 99%

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Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns

Jarvis

Rivas

et al. 2013

J of Comparative Neurology

168

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The last two authors contributed equally in co-supervising the project and conducting experiments. The second and last authors began this project originally as part of their graduate theses. ROLE OF AUTHORSEDJ, CCC, and KW performed experiments, quantifications, analyses, and wrote the article; JY, AP, CCC performed the computational analyses; MVR, HH, GF, OW, SCJ, ERJ, LK, SB, and ME performed gene expression experiments. SCJ also generated the 3D images and movies. AEPP processed and quantified images. CS and EH processed tissues and performed cell density measurements. HM helped co-supervise experiments.Additional Supporting Information may be found in the online version of this article. Detailed histological data from this article are available as virtual slides or whole-slide images using Biolucida Cloud image streaming technology from MBF Bioscience. The collection can be accessed at http://Wiley.Biolucida.net/JCN521-16Jarvis_Chen. All supporting figures and videos are located at: https://www.dropbox.com/sh/hl97l6a5zzxo54o/0MVQw0_epr NIH Public Access AbstractBased on quantitative cluster analyses of 52 constitutively expressed or behaviorally regulated genes in 23 brain regions, we present a global view of telencephalic organization of birds. The patterns of constitutively expressed genes revealed a partial mirror image organization of three major cell populations that wrap above, around, and below the ventricle and adjacent lamina through the mesopallium. The patterns of behaviorally regulated genes revealed functional columns of activation across boundaries of these cell populations, reminiscent of columns through layers of the mammalian cortex. The avian functionally regulated columns were of two types: those above the ventricle and associated mesopallial lamina, formed by our revised dorsal mesopallium, hyperpallium, and intercalated hyperpallium; and those below the ventricle, formed by our revised ventral mesopallium, nidopallium, and intercalated nidopallium. Based on these findings and known connectivity, we propose that the avian pallium has four major cell populations similar to those in mammalian cortex and some parts of the amygdala: 1) a primary sensory input population (intercalated pallium); 2) a secondary intrapallial population (nidopallium/hyperpallium); 3) a tertiary intrapallial population (mesopallium); and 4) a quaternary output population (the arcopallium). Each population contributes portions to columns that control different sensory or motor systems. We suggest that this organization of cell groups forms by expansion of contiguous developmental cell domains that wrap around the lateral ventricle and its extension through the middle of the mesopallium. We believe that the position of the lateral ventricle and its associated mesopallium lamina has resulted in a conceptual barrier to recognizing related cell groups across its border, thereby confounding our understanding of homologies with mammals. INDEXING TERMSforebrain; brain pathways; brain organization; neural activity; motor b...

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“…Karten [6,10], Reiner et al [11], Kuenzel et al [12] using various connectional and histochemical methods, demonstrated that only a limited portion of the avian telencephalon shared common properties with the mammalian basal ganglia. This was confined to the basal ventricular ridge (BVR) of the telencephalon.…”

Section: What Are the Boundaries Of The Basal Ganglia In Birds?mentioning

confidence: 99%

Vertebrate brains and evolutionary connectomics: on the origins of the mammalian ‘neocortex’

Karten¹

2015

Phil. Trans. R. Soc. B

114

105

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One contribution of 16 to a discussion meeting issue 'Origin and evolution of the nervous system'. The organization of the non-mammalian forebrain had long puzzled neurobiologists. Unlike typical mammalian brains, the telencephalon is not organized in a laminated 'cortical' manner, with distinct cortical areas dedicated to individual sensory modalities or motor functions. The two major regions of the telencephalon, the basal ventricular ridge (BVR) and the dorsal ventricular ridge (DVR), were loosely referred to as being akin to the mammalian basal ganglia. The telencephalon of non-mammalian vertebrates appears to consist of multiple 'subcortical' groups of cells. Analysis of the nuclear organization of the avian brain, its connections, molecular properties and physiology, and organization of its pattern of circuitry and function relative to that of mammals, collectively referred to as 'evolutionary connectomics', revealed that only a restricted portion of the BVR is homologous to the basal ganglia of mammals. The remaining dorsal regions of the DVR, wulst and arcopallium of the avian brain contain telencephalic inputs and outputs remarkably similar to those of the individual layers of the mammalian 'neocortex', hippocampus and amygdala, with instances of internuclear connections strikingly similar to those found between cortical layers and within radial 'columns' in the mammalian sensory and motor cortices. The molecular properties of these 'nuclei' in birds and reptiles are similar to those of the corresponding layers of the mammalian neocortex. The fundamental pathways and cell groups of the auditory, visual and somatosensory systems of the thalamus and telencephalon are homologous at the cellular, circuit, network and gene levels, and are of great antiquity. A proposed altered migration of these homologous neurons and circuits during development is offered as a mechanism that may account for the altered configuration of mammalian telencephalae.

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The avian subpallium: New insights into structural and functional subdivisions occupying the lateral subpallial wall and their embryological origins

Cited by 83 publications

References 351 publications

Oxytocin-like receptors mediate pair bonding in a socially monogamous songbird

Oxytocin-like receptors mediate pair bonding in a socially monogamous songbird

Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns

Vertebrate brains and evolutionary connectomics: on the origins of the mammalian ‘neocortex’

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