BackgroundAn azygos lobe is a rare anatomic variant of the lung which may be misdiagnosed as other pathological conditions. This study aimed to summarize the clinical characteristics and imaging manifestations of azygos lobe in children, which will be helpful for reasonable management and counseling of their families. Children with imaging ndings of azygos lobe from West China Second University Hospital of Sichuan University (Chengdu, China) between November 2008 and February 2019 were enrolled in the study. Clinical and radiologic characteristics of these patients were collected and analyzed.
ResultsIn total, 50 patients were included. 28% children were diagnosed as azygos lobe incidentally. The other 72% cases were diagnosed when they manifested respiratory symptoms including cough (18/50, 36%), fever (17/50, 34%), wheezing (9/50, 18%), dyspnea (7/50, 14%), and cyanosis (4/50, 8%). Congenital heart disease, Down syndrome, and other respiratory malformations were also found in a small proportion of these patients. In our study, all cases with azygos lobe had the right lung involved. Other imaging manifestations of these cases consisted of increased marking and in ltrates in the lung elds, local emphysema, consolidation, and atelectasis et al. Among the patients, only 8 patients (16%) diagnosed as azygos lobe infection. Compared with the non-infected group,there were no valuable risk factors related to the azygos lobe infection. And all the children with azygos lobe infection were cured after reasonable anti-infective treatment.
ConclusionChildren with azygos lobe were diagnosed mostly because of respiratory symptoms and these children had a good prognosis after resonable treatment. Only a small number of patients suffered from azygos lobe infection. Some of the patients with azygos lobe were found to have other organ malformations as well, which needed further monitoring and study.