“…This indicates that COL4 has important functions in plants besides flowering control, similar to other COLs and BBX family members. Recent publications discuss a linkage between COLs and BBX proteins being involved in plant developmental processes spanning over transition to flowering, seedling de-etiolation, photomorphogenesis, responses to antibiotic stress and shade avoidance, plant architecture, e.g., branching, circadian clock regulations and hormone signaling (Ledger et al, 2001; Cheng and Wang, 2005; Datta et al, 2006; Hassidim et al, 2009; Wang et al, 2013; Wang and Dehesh, 2015; Graeff et al, 2016; Tripathi et al, 2016, for review see: Vaishak et al, 2019). The COLs, especially CO, form heterodimers with other BBX proteins while being mediated into larger protein complexes and inactivated that subsequently alters the flowering habit.…”