The Bachman Intradermal Reaction in Human Trichinosis

Some Recent Developments in Helminthology

“…There seems general agreement that the immediate reaction is the one more constantly given in Trichinella infections, though Maternowska [31] finds that the delayed reaction is dominant in infections of long standing. Kilduffe [25] found considerable ambiguity in the intradermal test and thought it a less valuable diagnostic aid than the presence of eosinophilia. But Friedlander [20] points out that [30] reported a positive intradermal reaction in 90% of trichinosis cases, the reaction appearing in from two to three weeks after infection.…”

On the Persistence of Eosinophilia, and on Immune Reactions in Human Trichinosis, Several Years after Recovery

“…Maternowska (1933) concludes that the intradermal reaction is specific and diagnostic in laboratory animals, man and swine. Kilduffe (1933), apparently unaware of the work of Augustine and Theiler, and of McCoy, Miller and Friedlander, and using the technique and criteria of Bachman (1928), obtained indifferent results with the intradermal test in man and concluded that it presents no practical advantages over the demonstration of an eosinophilia. Friedlander (1934) draws attention to the fact that Kilduffe attempted to make use of the delayed reaction and a 1: 100 dilution of the antigen and not of the immediate reaction with the greatly diluted antigen, which gave such excellent results in the hands of other workers.…”