The bactericidal efficiency of sodium hypochlorite as an endodontic irrigant

Shih, Min‐Hsiung; Marshall, F. J.; Rosen, Samuel

doi:10.1016/0030-4220(70)90473-1

Cited by 152 publications

(85 citation statements)

References 8 publications

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“…In another study in which a similar methodology was used, Shih et al (20) tested different dilutions of Clorox  with suspensions of Streptococcus faecalis and S. aureus. Bacteria elimination was demonstrated after 30 s of contact with non-diluted Clorox and dilutions of 1:10, 1:100 and 1:1000.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial activity of different concentrations of NaOCl and chlorhexidine using a contact test

Sassone

Fidel

et al. 2003

Braz. Dent. J.

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The purpose of this study was to analyze the in vitro antimicrobial activity of sodium hypochlorite (1% and 5%) and chlorhexidine (0.12%, 0.5% and 1%). Bacterial samples (ATCC) of Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Porphyromonas gingivalis and Fusobacterium nucleatum were submitted to a contact test. Solutions were evaluated at different time intervals: immediately, 5 min, 15 min, and 30 min after contact and repeated 10 times. The results of the contact test showed that 0.12% chlorhexidine did not eliminate E. faecalis at any time interval, while 0.5% and 1% chlorhexidine and 1% and 5% sodium hypochlorite did. These results permit us to conclude that to obtain better antimicrobial activity, chlorhexidine in a concentration greater than 0.12% should be used.

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Section: Discussionmentioning

confidence: 99%

Antimicrobial activity of different concentrations of NaOCl and chlorhexidine using a contact test

Sassone

Fidel

et al. 2003

Braz. Dent. J.

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“…Higher concentrations have been reported to be more effective by using agar diffusion tests. [21][22][23] However, direct extrapolation to the clinical situation of agar diffusion test should be treated with caution. When used in contaminated canals of extracted teeth, Siqueira et al 24 found no difference in the antibacterial effect of 1%, 2.5%, and 5.2% NaOCl.…”

mentioning

confidence: 99%

The antimicrobial effects of root canal irrigation and medication

Karim

Kennedy

Hussey

2007

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an

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“…It has been recommended as an irrigant solution in the treatment of infected root canals because of its well-known bactericidal action [10,11,12]. The major disadvantages of NaOCl are: (a) significant toxicity when injected into peri-radicular tissues (b) disagreeable smell and taste (c) risk of bleaching clothes (d) corrosion of metal objects [13] (e) inability to remove smear layer when used alone [14,15].…”

Section: Imentioning

confidence: 99%