The Bambuí health and ageing study (BHAS): methodological approach and preliminary results of a population-based cohort study of the elderly in Brazil

Costa, Maria Fernanda Lima e; Uchôa, Elizabeth; Guerra, Henrique Leonardo; Firmo, Josélia O. A.; Vidigal, Pedro Guatimosim; Barreto, Sandhi Maria

doi:10.1590/s0034-89102000000200005

Cited by 136 publications

(79 citation statements)

References 15 publications

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“…The prevalence of hypertension (61.5%) was close to that described for the North American elderly (~60%) (23), as well as the prevalence of some traditional risk factors (24). A detailed description of the study design and methods has been published elsewhere (25).…”

Section: The Bambuí Health Ageing Study (Bhas)mentioning

confidence: 53%

Association of ApoE polymorphisms with prevalent hypertension in 1406 older adults: the Bambuí Health Aging Study (BHAS)

Fuzikawa

Peixoto

Taufer

et al. 2008

Braz J Med Biol Res

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Apolipoprotein E (ApoE) polymorphism influences lipid metabolism, but its association with arterial hypertension is controversial. The objective of this study was to examine the association between ApoE polymorphism and prevalent hypertension in a large unselected population of older adults. Participants from the baseline of the Bambuí Health Aging Study whose ApoE genes had been genotyped were selected for this study (N = 1406, aged 60-95 years). These subjects represented 80.7% of the total elderly residents in Bambuí city, MG, Brazil. Hypertension was defined as a systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥90 mmHg, or the use of anti-hypertensive medication. The exposure variable was the ApoE genotype as follows: ε3 carriers, ε3ε3; ε2 carriers, ε2ε2 or ε2ε3, and ε4 carriers, ε3ε4 or ε4ε4. Potential confounding variables were age, gender, traditional cardiovascular risk factors, uric acid, and creatinine levels. The prevalence of hypertension was 61.3%. Compared with the ε3 homozygotes, neither the ε2 nor the ε4 carrier status was associated with hypertension (adjusted prevalence ratios = 0.94, 95%CI = 0.83-1.07 and 0.98, 0.89-1.07, respectively). On the other hand, the ε2 allele carriers had lower LDL cholesterol levels (P < 0.001) and the ε4 carriers had higher LDL cholesterol levels (P = 0.036). This study provides epidemiologic evidence that the ApoE genotype is not associated with prevalent hypertension in old age.

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Section: The Bambuí Health Ageing Study (Bhas)mentioning

confidence: 53%

Association of ApoE polymorphisms with prevalent hypertension in 1406 older adults: the Bambuí Health Aging Study (BHAS)

Fuzikawa

Peixoto

Taufer

et al. 2008

Braz J Med Biol Res

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“…8 A total of 17 elderly individuals participated in the study (≥ 70 years of age), of both sexes (nine women and nine men), and with varied socioeconomic levels. Criteria for inclusion of participants were as follows: to agree to participate in the study and to be able to give clear information.…”

Section: Introduction Methodological Proceduresmentioning

confidence: 99%

Papel da autonomia na auto-avaliação da saúde do idoso

et al. 2010

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OBJETIVO: Compreender os significados atribuídos à auto-avaliação da saúde do idoso. PROCEDIMENTOS METODOLÓGICOS: Estudo qualitativo, realizado com 17 idosos (> 70 anos) de ambos os sexos residentes em Bambuí, MG, em 2008. Foi utilizada abordagem antropológica baseada no modelo de signos, significados e ações que relaciona ações individuais, códigos culturais e contexto macrossocial. Foram realizadas entrevistas semi-estruturadas centradas na auto-avaliação da saúde, descrição de saúde "boa" e saúde "ruim" e nos critérios utilizados pelos idosos na auto-avaliação da saúde. ANÁLISE DOS RESULTADOS: A idéia organizadora dos relatos vincula a autoavaliação da saúde do idoso às lógicas "participar da vida" e "ancoragem à vida". A primeira tem a autonomia como fio condutor, englobando as seguintes categorias: permanecer ativo dentro das capacidades funcionais instrumentais avançadas, ser dono da própria vida (como oposição a ser dependente), ser capaz de resolver problemas e poder agir como desejar. A segunda lógica unifica as seguintes categorias: capacidade de interação, estar engajado em relações significativas e poder contar com familiares, amigos ou vizinhos. CONCLUSÕES: A saúde é entendida pelos idosos como ter autonomia no exercício de competências funcionais demandadas pela sociedade, tais como capacidade de responder às obrigações familiares e capacidade de desempenhar papéis sociais. Ao definir sua saúde como boa ou razoável, o idoso não se caracteriza como pessoa livre de doenças, mas como sujeito capaz de agir sobre o ambiente.

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“…Life expectancy was 70.2 years and the leading death causes among the elderly were cerebrovascular diseases, Chagas' disease and ischemic heart disease. 22 All the city inhabitants aged 60 years or older on the first of January of 1997 were identified through census and selected to constitute the baseline of the cohort study. Of the 1,742 dwellers in the selected age group, 1,606 (92.2%) participated in the baseline study and were selected for the present study.…”

Section: Study Area and Populationmentioning

confidence: 99%

“…If the selected older adult was not able to respond to the questionnaire due to health problems or cognitive deficit, a close relative or caregiver responded instead (5.6% of the interviews were answered by a proxy). 22 The dependent variable of the study was the use of benzodiazepines. For its construction, information was obtained about the use of any medication in the last 90 days.…”

Section: Variablesmentioning

confidence: 99%

Prevalence and sociodemographic characteristics associated with benzodiazepines use among community dwelling older adults: the Bambuí Health and Aging Study (BHAS)

Alvarenga

Filho

Firmo

et al. 2007

Rev. Bras. Psiquiatr.

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Introduction Fear or anxious apprehension are emotional responses to danger or threat. For thousands of years humans have used diverse substances to alleviate this negative emotional state. One of the first tranquilizers used, and which continues to be consumed until today, is alcohol; others followed, such as barbiturates, bromides and meprobamates. 1 Since they were released in the market in 1960, the benzodiazepines became the most prescribed drugs and the most used to combat anxiety and insomnia in the whole world.2 This use stemmed from their efficiency, security, and lower potential to cause dependence, their tolerance as well as wide therapeutic applicability. 3 Nonetheless, the use of benzodiazepines has been associated with several adverse effects, such as motor disturbances, falls, daytime sleepiness and cognitive decline. The modifications in metabolism which accompany the ageing process make the elderly an especially vulnerable age group to these undesirable medication effects, 3 which are even worse when long half-life benzodiazepines are used for prolonged periods, especially when not accompanied by an adequate clinical monitoring. 4 The use of benzodiazepines is frequent among the elderly. Although a decrease in prescribing benzodiazepines for the elderly has been observed in some studies, 5,6 population-based studies continue to demonstrate high prevalences in the consumption of these medications in developed countries, and levels ranged from 20.0% in Canada 7 to 31.9% in France.8 With respect to the type of benzodiazepines most used, there is a diversity of results in different countries.8-10 It has been described that female gender is the sociodemographic characteristic most consistently found to be associated with the use of benzodiazepines among the elderly. 5,6,8,9,11 Brazilian epidemiological studies on the use of benzodiazepines among the elderly dealt with selected populations and/or investigated specific associations, such as the occurrence of falls.12-15 Populationbased studies on the consumption of these medications have been accomplished on younger individuals, 16,17 and the benzodiazepine consumption was investigated in a much wider context, which was the use of psychopharmacs. [18][19][20] The population-based studies showed benzodiazepines as the most commonly used psychopharmacs in the adult population, [17][18][19][20] and among these, Diazepam was the most used chemical substance. 16,18,19 In these studies, the consumption of benzodiazepines was higher among women, 16,17 among older subjects and among the wealthy. 17To our knowledge, there are no Brazilian studies on the profile of use of benzodiazepines among community-dwelling older adults. As the use of these medications among the elderly is more frequent and involves greater risks and taking into consideration the rapid aging of the Brazilian population, 21 it is important to investigate this question in greater detail in this country.The present study has the following objectives: 1) to determine the prevalence of be...

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The Bambuí health and ageing study (BHAS): methodological approach and preliminary results of a population-based cohort study of the elderly in Brazil

Cited by 136 publications

References 15 publications

Association of ApoE polymorphisms with prevalent hypertension in 1406 older adults: the Bambuí Health Aging Study (BHAS)

Association of ApoE polymorphisms with prevalent hypertension in 1406 older adults: the Bambuí Health Aging Study (BHAS)

Papel da autonomia na auto-avaliação da saúde do idoso

Prevalence and sociodemographic characteristics associated with benzodiazepines use among community dwelling older adults: the Bambuí Health and Aging Study (BHAS)

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