The begomovirus–host interplay in viral replication and movement

Chodon, Aparna; Karanthamalai, Jeyalakshmi; Pandi, Gopal; Tennyson, Jebasingh

doi:10.1016/b978-0-323-90587-9.00001-8

Cited by 4 publications

(2 citation statements)

References 181 publications

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“…The Rep has been found in interaction with several host proteins to facilitate viral replisome complex for DNA replication and repair system, proper cell division and signal transduction (Campos-Olivaset al , 2002). Another viral protein REn modulates Rep binding with the host protein in the nucleus, to regulate DNA repair and recombination leading to the controlled cell cycle machinery (Chodon et al , 2022) (Hanley-Bowdoin et al , 2004). Initially, Rep binds with a highly conserved plant protein proliferating cell nuclear antigen (PCNA), that overexpresses transcription level of geminivirus in infected cells (Nagar et al , 1995).…”

Section: Plant Nucleus and Rep-ren Complexmentioning

confidence: 99%

Functional role of Geminivirus encoded proteins in the host: Past and Present

Kamal,

Zafar,

Razzaq

et al. 2024

Preprint

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During plant-pathogen interaction, plant exhibits a strong defense system utilizing diverse groups of proteins to suppress the infection and subsequent establishment of the pathogen. However, in response, pathogens trigger an anti-silencing mechanism to overcome the host defense machinery. Among plant viruses, geminiviruses are the second largest virus family with a worldwide distribution and continue to be production constraints to food, feed, and fiber crops. These viruses are spread by a diverse group of insects, predominantly by whiteflies, and are characterized by a single-stranded DNA (ssDNA) genome coding for four to eight proteins that facilitate viral infection. The most effective means to managing these viruses is through an integrated disease management strategy that includes virus-resistant cultivars, vector management, and cultural practices. Dynamic changes in this virus family enable the species to manipulate their genome organization to respond to external changes in the environment. Therefore, the evolutionary nature of geminiviruses leads to new and novel approaches for developing virus-resistant cultivars and it is essential to study molecular ecology and evolution of geminiviruses. This review summarizes the multifunctionality of each geminivirus-encoded protein. These protein-based interactions trigger the abrupt changes in the host methyl cycle and signaling pathways that turn over protein normal production and impair the plant antiviral defense system. Studying these geminivirus interactions localized at cytoplasm-nucleus could reveal a more clear picture of host-pathogen relation. Data collected from this antagonistic relationship among geminivirus, vector, and its host, will provide extensive knowledge on their virulence mode and diversity with climate change

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Section: Plant Nucleus and Rep-ren Complexmentioning

confidence: 99%

Functional role of Geminivirus encoded proteins in the host: Past and Present

Kamal,

Zafar,

Razzaq

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…[136][137][138][139] Another viral protein REn modulates Rep binding with the host protein in the nucleus to regulate DNA repair and recombination leading to the controlled cell cycle machinery (Hanley-Bowdoin et al, 2004). [140] Initially, Rep binds with a highly conserved plant protein proliferating cell nuclear antigen (PCNA) that overexpresses transcription level of geminivirus in infected cells. [141] A large subunit, replication factor C complex modulates PCNA binding with Rep to hold ssDNA for rolling circle-replication.…”

Section: Role Of Rep-ren Complex In Plant Nucleusmentioning

confidence: 99%

Functional role of geminivirus encoded proteins in the host: Past and present

Kamal,

Zafar,

Razzaq

et al. 2024

Biotechnology Journal

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During plant–pathogen interaction, plant exhibits a strong defense system utilizing diverse groups of proteins to suppress the infection and subsequent establishment of the pathogen. However, in response, pathogens trigger an anti‐silencing mechanism to overcome the host defense machinery. Among plant viruses, geminiviruses are the second largest virus family with a worldwide distribution and continue to be production constraints to food, feed, and fiber crops. These viruses are spread by a diverse group of insects, predominantly by whiteflies, and are characterized by a single‐stranded DNA (ssDNA) genome coding for four to eight proteins that facilitate viral infection. The most effective means to managing these viruses is through an integrated disease management strategy that includes virus‐resistant cultivars, vector management, and cultural practices. Dynamic changes in this virus family enable the species to manipulate their genome organization to respond to external changes in the environment. Therefore, the evolutionary nature of geminiviruses leads to new and novel approaches for developing virus‐resistant cultivars and it is essential to study molecular ecology and evolution of geminiviruses. This review summarizes the multifunctionality of each geminivirus‐encoded protein. These protein‐based interactions trigger the abrupt changes in the host methyl cycle and signaling pathways that turn over protein normal production and impair the plant antiviral defense system. Studying these geminivirus interactions localized at cytoplasm‐nucleus could reveal a more clear picture of host–pathogen relation. Data collected from this antagonistic relationship among geminivirus, vector, and its host, will provide extensive knowledge on their virulence mode and diversity with climate change.

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Replication Assay of Begomovirus in Arabidopsis Protoplasts

Martins,

Fontes

2023

Methods in Molecular Biology

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The begomovirus–host interplay in viral replication and movement

Cited by 4 publications

References 181 publications

Functional role of Geminivirus encoded proteins in the host: Past and Present

Functional role of Geminivirus encoded proteins in the host: Past and Present

Functional role of geminivirus encoded proteins in the host: Past and present

Replication Assay of Begomovirus in Arabidopsis Protoplasts

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