The Beneficial Effect of 20% Sunflower Seed Oil Cream on Mild Atopic Dermatitis in Children

Abstract

Objective: The objective of this study was to evaluate the beneficial effect of topical applications of 20% sunflower seed oil (SSO) in decreasing the transepidermal water loss (TEWL) and scoring of atopic dermatitis (SCORAD) index value in mild atopic dermatitis (AD) pediatric patients in Bandung, Indonesia.
 Methods: This was a randomized study involving 20 children with mild AD (SCORAD<25) in Bandung, Indonesia. They were divided into 2 groups: the experimental group treated with 20% SSO cream and the control group treated with a common moisturizing cream for four weeks. The TEWL score including SCORAD index was evaluated at baseline, week 1, week 2, and week 4.
 Results: A total of 20 participants completed the study. In the first week, the control group had TEWL score decrement by 36.62% while the experimental group by 28.89% (p=0.88). In the fourth week, the TEWL decrements of the experimental and control group were by 56.94% and 52.50%, respectively (p=0.20), and this was followed by an improvement of SCORAD index in both treatment groups.
 Conclusion: The 20% SSO cream has a beneficial effect in decreasing the TEWL score and improving SCORAD indices. Therefore, it can be considered as an alternative treatment for mild AD among children.

Complementary and alternative medicine treatments for common skin diseases: A systematic review and meta-analysis

“…( Tables II and III ). 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46

Fig 2 The PRISMA flow diagram. PRISMA , Preferred reporting items for systematic reviews and meta-analyses.

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“…Scoring of atopic dermatitis (SCORAD) in AD. Two studies including 98 patients with AD examined the efficacy of treatment with sunflower seed oil (SSO) 39,40 (Table III). The primary outcome measured was improvement of the scoring of atopic dermatitis (SCORAD) in AD score.…”