A field experiment was conducted in sandy soil at Wadi El-Natrun region, Egypt (30°23'19.89˝ N latitude and 30°21'41.06˝ E longitude) during 2018 and 2019 seasons to evaluate growth, quality, productivity and water use efficiently of four sweet sorghum varieties (Sorghum Bicolor L. Moench) under the influence of two types of irrigation sources (fish farm waste water and well ground water irrigation) in addition to study the effect of spraying three concentration of gibberellic acid (zero, 200 and 400 ppm). The results revealed that fish farm waste water irrigation was significantly more efficient than well ground water irrigation on vegetative characters (stalk length and diameters (cm)), yield (gross and stripped stalk yields (ton/fed)) and water use efficiency (WUE of gross and stripped yields (kg/m 3 )) in both seasons. Vice versa, the irrigation by well ground water surpassed the irrigation by waste water fish farm in quality parameters (juice and syrup extraction %) and (sucrose and purity %), in addition significant increases were detected in vegetative characters, yield and water use efficiency by increasing gibberellic acid (GA3) concentrations from zero up to 400 ppm during both seasons. On the other hand, quality parameters of sweet sorghum plants decreased by increasing gibberellic acid (GA3) concentrations from zero up to 400 ppm in both seasons. Sweet sorghum AGSC3 variety over passed the other varieties with respect to stalk length and diameters (cm), yields of gross and stripped stalks yield (ton/fed) and water use efficiency (WUE) of gross and stripped stalks yield (kg/m 3 ) in both seasons. While, results showed that Ramada variety surpassed significantly the other studied varieties under this study in respect to juice and syrup extraction (%) as well as sucrose and purity (%) in both seasons.Keywords: fish farm waste water, gibberellic acid, new reclaimed area, sweet sorghum, water resources.