The Benefits of Plant Extracts for Human Health

Proestos, Charalampos

doi:10.3390/foods9111653

Cited by 35 publications

(19 citation statements)

References 18 publications

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“…A number of scientific evidence supports the use of plant extracts to promote good health and wellbeing [ 26 ]. However, traditional methods for plant extraction are energy-consuming and environmentally unfriendly [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

A Green Extraction Method to Achieve the Highest Yield of Limonin and Hesperidin from Lime Peel Powder (Citrus aurantifolia)

2022

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Green extraction is aimed at reducing energy consumption by using renewable plant sources and environmentally friendly bio-solvents. Lime (Citrus aurantifolia) is a rich source of flavonoids (e.g., hesperidin) and limonoids (e.g., limonin). Manufacturing of lime products (e.g., lime juice) yields a considerable amount of lime peel as food waste that should be comprehensively exploited. The aim of this study was to develop a green and simple extraction method to acquire the highest yield of both limonin and hesperidin from the lime peel. The study method included ethanolic-aqueous extraction and variable factors, i.e., ethanol concentrations, pH values of solvent, and extraction temperature. The response surface methodology was used to optimize extraction conditions. The concentrations of limonin and hesperidin were determined by using UHPLC-MS/MS. Results showed that the yields of limonin and hesperidin significantly depended on ethanol concentrations and extraction temperature, while pH value had the least effect. The optimal extraction condition with the highest amounts of limonin and hesperidin was 80% ethanol at pH 7, 50 °C, which yields 2.072 and 3.353 mg/g of limonin and hesperidin, respectively. This study illustrates a green extraction process using food waste, e.g., lime peel, as an energy-saving source and ethanol as a bio-solvent to achieve the highest amount of double bioactive compounds.

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Section: Discussionmentioning

confidence: 99%

A Green Extraction Method to Achieve the Highest Yield of Limonin and Hesperidin from Lime Peel Powder (Citrus aurantifolia)

2022

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“…In recent times, the tendency to use medicinal plants has continued to grow, because of their antioxidant properties and health-related effects [25]. Healing properties of medicinal plants are related to the presence of vitamins, minerals and various phenolic compounds in plants.…”

Section: Discussionmentioning

confidence: 99%

Determination and Evaluating the Antioxidant Properties of Ziziphus nummularia (Burm.f.) Wight & Arn., Crataegus pontica K.Koch and Scrophularia striata Boiss

Dokhani

Nazer²,

skokri³

et al. 2022

Egyptian Journal of Veterinary Sciences

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R ESEARCHERS have shown an increasing attention to the use of medicinal plants because of their beneficial effect on human health. The antioxidant properties of medicinal plants is a strong reason to use them in the food and pharmaceutical industries. Hence, the aim of this study was to evaluate the antioxidant properties of Ziziphus nummularia, Crataegus pontica and Scrophularia striata. Aerial parts of Ziziphus nummularia, Crataegus pontica and Scrophularia striata were dried and ground. Then, plant samples were prepared using homogenizing plant powders in methanol solution. Finally, the total antioxidant capacity of the plants was assessed by ferric iron reducing antioxidant power (FRAP) assay.The results indicated that the total antioxidant capacity was found as 3.16, 2.95 and 1.14 mmol Fe 2+ /L for Ziziphus nummularia, Crataegus pontica and Scrophularia striata, respectively. According to our results, Ziziphus nummularia, Crataegus pontica and Scrophularia striata showed a potent antioxidant activity. It is recommended that utilization of Ziziphus nummularia, Crataegus pontica and Scrophularia striata in food and pharmaceutical industries could possibly possess beneficial health effects.

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“…Many diseases have been treated and eradicated due to the evolution of medicine and, more particularly, herbal medicine, which served as an important source of bioactive compounds (Proestos et al, 2020). Previous studies (Ugur et al, 2009;Escher et al, 2018) made on two Centaurea species; namely, C. ensiformis and C. cyanus showed significant antioxidant activities of this species with dose-dependent effect and suspected that the actual phenolic, flavonoids, and anthocyanins compounds identified in their extracts are responsible for the biological effect.…”

Section: Discussionmentioning

confidence: 99%

In vitro assessment of antioxidant, anti-inflammatory, neuroprotective and antimicrobial activities of Centaurea tougourensis Boiss. & Reut.

Bensaad¹,

Dassamiour²,

Hambaba³

et al. 2021

J Pharm Pharmacogn Res

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Context: More than 500 Centaurea species compose the Asteraceae family, and most of the recent studies made on the species of this genus proved their pharmacological potential, especially to treat chronic illnesses. Aims: To evaluate for the first time the antioxidant, anti-inflammatory, neuroprotective and anti-microbial properties of the n-butanol (n-BuOH) and ethyl acetate (EA) extracts of the aerial part of Centaurea tougourensis. Methods: The antioxidant activity was determined by ABTS, galvinoxyl radical, phenanthroline, and reducing power assays, while the anti-inflammatory effects were assessed by heat-induced hemolysis and egg albumin denaturation assays. The neuroprotective activity was assessed against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) and the anti-microbial activity by the agar disk diffusion method. Results: Both extracts possess a great antioxidant capacity, but it was considered higher in the n-BuOH extract with respective IC50 values of 8.04 ± 0.21 μg/mL in ABTS assay and 4.25 ± 0.6 μg/mL in GOR assay, while the A0.50 values were 4.46 ± 0.55 μg/mL in phenanthroline assay and 11.16 ± 0.64 μg/mL in reducing power assay. The n-BuOH extract also showed a remarkable anti-inflammatory activity with an EC50 of 120.81 ± 0.2 μg/mL in egg albumin denaturation assay and 154.15 ± 0.14 μg/mL in heat-induced hemolysis assay. The neuroprotective activity of the n-BuOH extract was very strong in both AChE and BChE inhibitory assays with respective IC50 values of 9.8 ± 0.62 μg/mL and 173.53 ± 0.04 μg/mL. EA extract was more active on microbial strains. Conclusions: These encouraging results showed once again the pharmacological potential of Centaurea species.

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The Benefits of Plant Extracts for Human Health

Abstract: Nature has always been, and still is, a source of foods and ingredients that are beneficial to human health [...]

Cited by 35 publications

References 18 publications

A Green Extraction Method to Achieve the Highest Yield of Limonin and Hesperidin from Lime Peel Powder (Citrus aurantifolia)

A Green Extraction Method to Achieve the Highest Yield of Limonin and Hesperidin from Lime Peel Powder (Citrus aurantifolia)

Determination and Evaluating the Antioxidant Properties of Ziziphus nummularia (Burm.f.) Wight & Arn., Crataegus pontica K.Koch and Scrophularia striata Boiss

In vitro assessment of antioxidant, anti-inflammatory, neuroprotective and antimicrobial activities of Centaurea tougourensis Boiss. & Reut.

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