The Best Evidence for the Prevention and Management of Lower Extremity Deep Venous Thrombosis After Gynecological Malignant Tumor Surgery: A Systematic Review and Network Meta-Analysis

Abstract

Background:To search and obtain the relevant evidence of prevention and management of lower extremity deep venous thrombosis (DVT) after gynecological malignant tumor operation and to summarize the relevant evidence.MethodsWe searched the JBI evidence summary, up to date, the national comprehensive cancer network of the United States, the guide library of the National Institute of clinical medicine of the United Kingdom, PubMed, the Chinese biomedical literature database, CNKI, Wanfang, and other relevant evidence on the prevention and management of DVT in patients with gynecological malignant tumors. It includes clinical practice guidelines, best practice information book, expert consensus, evidence summary, original research, etc. The retrieval time limit is from database establishment till August 20, 2021. Two researchers independently evaluated the literature quality, combined with professional judgment, and extracted the literature that met the standards.ResultsFinally, 18 literatures were included, including eight guidelines, three evidence summaries, four systematic evaluations, two expert consensuses, and one best practice information volume. A total of 26 pieces of the best evidence on the prevention and management of postoperative venous thrombosis in gynecological malignant tumors were summarized. It includes risk assessment, drug prevention, mechanical prevention, management strategy, and health education.ConclusionThis study summarized the best evidence of risk, prevention, and health management of DVT in postoperative patients with gynecological malignant tumors to provide evidence-based basis for clinical nurses and to improve the nursing level.

A nomogram model for predicting lower extremity deep vein thrombosis after gynecologic laparoscopic surgery: a retrospective cohort study

“…Laparoscopic surgery is a commonly employed minimally invasive technique within gynecology. Nonetheless, the incidence of LEDVT remains high due to the utilization of pneumoperitoneum and the patient’s position during surgery ( Hu et al, 2022 ; Wu & Cheng, 2020 ). A previous study displayed the incidence of LEDVT subsequent to gynecologic laparoscopic surgery to be 7.6–11.55% ( Tian & Li, 2021 ).…”

“…Many previous studies have reported that their model has considerable predictive value for LEDVT ( Hu et al, 2022 ; Tian & Li, 2021 ; Wu & Cheng, 2020 ). However, they did not take into account the relevant preoperative biochemical indicators.…”

Risk factors analysis and the establishment of nomogram prediction model for PICC-related venous thrombosis in patients with lymphoma: a double-center cohort-based case-control study

“…This, in turn, leads to venous dilation, endothelial impairment, and the accumulation of coagulation factors that trigger the activation of the coagulation system, ultimately facilitating the development of thrombus. Consequently, numerous scholarly works have emphasized the significance of health education pertaining to mechanical prophylaxis, including healthcare practitioners advising patients to engage in upper limb relaxation and clenching at the site of peripheral central venous catheter insertion as a preventive measure against the formation of PICC-RVTE (20,21). Furthermore, our study specifically examined the association between a history of thrombosis within the previous 12 months and the formation of PICC-RVTE.…”