The biopharmaceutics and oral bioavailability of two forms of oxytetracycline to the white shrimp, Litopenaeus setiferus

Reed, Lou Ann; Siewicki, Thomas C.; Shah, Jaymin

doi:10.1016/j.aquaculture.2006.03.029

Cited by 28 publications

(24 citation statements)

References 31 publications

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“…This is in agreement with the findings of Mohney et al [57]. Unlike vertebrates, for which metabolism and excretion of drugs take place in separate organs such as the liver and kidney, shrimp possess only a hepatopancreas, which plays several roles, such as collection, metabolism, and excretion of antibiotics [62]. Chiayvareesajja et al [63] proposed the hepatopancreas to be the major route for OTC elimination (60%) in whiteleg shrimp.…”

Section: Antibiotic Residues In Penaeid Shrimpsupporting

confidence: 87%

Effects of pesticides and antibiotics on penaeid shrimp with special emphases on behavioral and biomarker responses

Silvestre

Phương

et al. 2010

Enviro Toxic and Chemistry

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Abstract-The purpose of the present study is to provide information on the current state of knowledge regarding the effects of pesticides and antibiotics used in aquaculture on penaeid shrimp, one of the most common aquatic products for human consumption, with a special emphasis on the use of behavioral, physiological, and biochemical response. These include behavior; feeding rate changes; respiration rate, oxygen consumption, and osmoregulation alterations; nucleic acids, protein, and glycogen synthesis; cholinesterase activity inhibition; ATPase activity; and oxidative stress responses. This paper also deals with residues of antibiotics and pesticides in penaeid shrimp. Antibiotics and pesticides used in aquaculture may have adverse effects on treated animals and human consumers health if they are not correctly used. As a complement to the measurement of antibiotic and pesticide residues in tissues, the use of behavioral and biomarker responses can provide more relevant biological information on the potential adverse effects of antibiotics and pesticides on penaeid shrimp health. Environ. Toxicol. Chem. 2010;29:929-938. # 2009 SETAC

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Section: Antibiotic Residues In Penaeid Shrimpsupporting

confidence: 87%

Effects of pesticides and antibiotics on penaeid shrimp with special emphases on behavioral and biomarker responses

Silvestre

Phương

et al. 2010

Enviro Toxic and Chemistry

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“…It has potential for use in farm-raised shrimp for the treatment of vibriosis like Vibrio alginolyticus and Vibrio harveyi. There are many studies on the pharmacokinetics and residues of OTC in marine and freshwater shrimp (Mohney et al 1997;Bermúdez-Almada et al 1999;Brillantes et al 2001;Uno 2002Uno , 2004Sangrungruang et al 2004;Reed et al 2004Reed et al , 2006Weifen et al 2004;Uno et al 2006;Poapolathep et al 2008a, b), but limited information of OTC dispositions in P. vannamei is available (Chiayvareesajja et al 2006;Nogueira-Lima et al 2006;Faroongsarng et al 2007;Gómez-Jimenez et al 2008). …”

Section: Introductionmentioning

confidence: 95%

Pharmacokinetics and bioavailability of oxytetracycline in vannamei shrimp (Penaeus vannamei) and the effect of processing on the residues in muscle and shell

Uno

Chaweepack²,

Ruangpan

2010

Aquacult Int

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The present study examined the pharmacokinetics and bioavailability of oxytetracycline (OTC) in vannamei shrimp (Penaeus vannamei) after intra-sinus (10 mg/kg) and oral (10 and 50 mg/kg) administration and also investigated the net changes of OTC residues in the shrimp after the thermal, acid and alkaline processing methods. The hemolymph concentrations of OTC after intra-sinus dosing were best described by a twocompartment open model. The oral bioavailability was found to be 48.2 and 43.6% at doses of 10 and 50 mg OTC/kg, respectively. The peak hemolymph concentrations after 10 and 50 mg OTC/kg doses were 3.37 and 17.4 lg/ml; the times to peak hemolymph concentrations were 7 and 10 h. The elimination half-lives were found to be 15.0 and 11.5 h for the low and high dose, respectively. The residual OTC was rapidly eliminated from muscle with the elimination half-life value of 19.4 and 15.4 h, respectively, for the groups treated with doses of 10 and 50 mg/kg. The residual OTC levels in the muscle fell below the MRL (0.2 lg/g) at 72 and 96-h post-dosing at dose levels of 10 or 50 mg/kg, respectively. Residual OTC levels in muscle and shell were approximately 20-50% lower in the thermal treatment such as boiling, baking and frying. By the acid treatment, OTC residues were reduced to [80%, while those were reduced to around 30% by alkaline treatment.

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“…From the samples of fish examined, the average rate of infection was 43.79%, including 15.03% of them as a bacterial infection and identified as Vibrio spp. Two methods were used for identification of Vibrio spp., the VITEK 2 system which detect only V. cholerae (10 isolates) with probability 98% and confidence, excellent identification, while the other isolates were failed to identify with it, so its identified depending upon their biochemical profiles (Table 3) as V. gazogenes (5), V. alginolyticus (24), V. costicola (4), V. furnisii (10) and V. diazotrophicus (7).…”

Section: Bacterial Diagnosismentioning

confidence: 99%

“…Oxytetracycline is widely used to treat bacterial infections in aquaculture farms, such as vibriosis and furunculosis [23,24]. In spite of that, many infected cases have been detected among fish, particularly common carp, and this is may be related to that, the an extensive use of antibiotics can cause the development of antibiotic-resistant pathogens which can infect both cultured animals as well as humans [25][26][27].…”

Section: Bacterial Diagnosismentioning

confidence: 99%

Vibrio Species Isolated from Farmed Fish in Basra City in Iraq

Al-Taee¹,

Khamees²,

Al-Shammari³

2017

J Aquac Res Development

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The biopharmaceutics and oral bioavailability of two forms of oxytetracycline to the white shrimp, Litopenaeus setiferus

Cited by 28 publications

References 31 publications

Effects of pesticides and antibiotics on penaeid shrimp with special emphases on behavioral and biomarker responses

Effects of pesticides and antibiotics on penaeid shrimp with special emphases on behavioral and biomarker responses

Pharmacokinetics and bioavailability of oxytetracycline in vannamei shrimp (Penaeus vannamei) and the effect of processing on the residues in muscle and shell

Vibrio Species Isolated from Farmed Fish in Basra City in Iraq

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