The Blink Reflex in Migraine

Bánk, J.; Bense, Erzsébet; Király, Cs

doi:10.1046/j.1468-2982.1992.1205289.x

Cited by 36 publications

(24 citation statements)

References 20 publications

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“…However, they did not indicate whether or not this study was performed during patient migraine attack or not. They stated that these findings could be presented as objective evidence of the involvement of trigeminal afferents and/or polysynaptic pathways in the brainstem of patients with migraine headache [29]. In the present study, right- and left-sided R1, as well as R2i and R2c latency values were compared with those of the control group, and significantly longer latencies were detected in the patient group, supporting role of trigeminovascular system in migraine.…”

Section: Discussionsupporting

confidence: 66%

Blink Reflex in migrane headache

Ünal¹,

Domaç

Boylu

et al. 2016

North Clin Istanbul

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OBJECTIVE:Activation of trigeminovascular system is thought to play an important role in migraine pathogenesis. Blink reflex (BR) test is an easy method to study the trigeminal system. Latencies recorded in BR test were evaluated to examine neurophysiological changes that occur in migraine patients.METHODS:A total of 40 patients diagnosed with migraine (9 with aura and 31 without aura) according to the International Headache Society (IHS) International Classification of Headache Disorders, 2nd edition, and 30 healthy control subjects were assessed using BR test. Supraorbital nerve was stimulated on each side, and unilateral early component (R1), and bilateral late component (R2) latencies were evaluated.RESULTS:Significantly longer latency values were recorded on both right and left sides (RR1 and LR1) as well as both ipsilateral and contralateral R2 on the left side (LR2i and LR2c) in the migraine group compared to the control group. Longer RR1 and LR1 latencies were found in patients with migraine who had an attack at the time of study (p<0.01). There was no statistically significant correlation between the location of pain and latencies in the interictal period (p>0.05). But significantly longer R1 and R2i latencies were found at the symptomatic side of patients examined during the headache attack (p=0.037 and p=0.028 respectively). There was no statistically significant correlation between the recorded latencies and gender, attack duration, attack frequency and migraine type (p>0.05).CONCLUSION:Results of BR test in the present study are thought to point to a dysfunction in brainstem and trigeminovascular connections of patients with migraine headache and support the trigeminovascular theory of migraine.

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Section: Discussionsupporting

confidence: 66%

Blink Reflex in migrane headache

Ünal¹,

Domaç

Boylu

et al. 2016

North Clin Istanbul

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“…These data indicate suppression of the brainstem interneurone part of the blink reflex during a migraine headache attack. (Avramidis et al 1998) The R2 latency differs statistically significantly between control subjects and migraine patients (Bánk et al 1992). The R1 and R2 latencies, amplitudes and areas of the basal blink reflex are similar in migraineurs ictally and between migraine attacks and also in control subjects.…”

Section: Blink Reflexmentioning

confidence: 87%

Where does a migraine attack originate? In the brainstem

et al. 2012

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Migraine is a common, paroxysmal, highly disabling primary headache disorder. The origin of migraine attacks is enigmatic. Numerous clinical and experimental results suggest that the activation of distinct brainstem nuclei is crucial in its pathogenesis, but the primary cause of this activation is not fully understood. We conclude that the initialization of a migraine attack can be explained as an altered function of the neuronal elements of the brainstem nuclei. In light of our findings and the literature data, we can assume that migraine is a subcortical disorder of a specific brainstem area.

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“…Only a few studies on the blink reflex have provided consistent results [4,23]. Due to the nociceptive nature of the R2 and R3 components of the blink reflex, they have received major attention.…”

Section: Discussionmentioning

confidence: 99%

Short latency trigemino-sternocleidomastoid response in patients with migraine

Nardone¹,

Tezzon²

2003

Journal of Neurology

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Our findings further support and emphasise the role of the trigeminal system in the pathogenesis of migraine. The bilateral location of the abnormalities suggests a centrally located dysfunction. Therefore, the trigemino-cervical reflex is sensitive in disclosing a disturbed brainstem activity and may be an index of neuronal activity in the human brainstem; moreover their assessment may help as valuable prognostic tool for predicting the efficacy of triptans therapy.

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The Blink Reflex in Migraine

Cited by 36 publications

References 20 publications

Blink Reflex in migrane headache

Blink Reflex in migrane headache

Where does a migraine attack originate? In the brainstem

Short latency trigemino-sternocleidomastoid response in patients with migraine

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