Highlights (3 to 5 bullet points, maximum 85 characters, including spaces, per bullet point, to be submitted in a separate editable file in the online submission system, using 'Highlights' in the file name). • Marine noise is a widespread source of pollution in the Mediterranean Sea • Noise pollution produces a multitude of impacts on marine fish and invertebrates • Marine noise pollution impacts individuals to ecosystems • A variety of measures could be adopted to mitigate marine noise pollution Abstract (max 150 words): Marine noise pollution (MNP) can cause a multitude of impacts on many organisms, but information is often scattered and general outcomes difficult to assess. We systematically reviewed the available knowledgeliterature about MNP impacts on Mediterranean fish and invertebrates. Both chronic and acute MNP produced by several human activities-e.g. maritime traffic, pile driving, air guns-were found to cause detectable effects on intraspecific communication, vital processes, physiology, behavioral patterns, health status and survival. These individual-based effects can extend to induce population-and ecosystem-wide alterations, especially when MNP impacts functionally important species, such as keystone predators and habitat forming species. Curbing the threats of MNP in the Mediterranean Sea is not an easya challenging task, but a variety of measures should could be adopted to mitigate MNP impacts. Successful measures will require more precise accurate information on impacts, and that effective management of MNP actually becomes a priority in the policy makers' agenda.