This special issue takes as its primary theoretical touchstone cultural, queer, and feminist theorist Gloria Anzaldúa's La Frontera (2007), a text that interrogated Anzaldúa's own 'mestiza consciousness' to theorise the multiplying and hybridising potential of the US-Mexico borderlands and the various forms of living that emerged within. Though her writing was always critically and politically engaged, resistance, for Anzaldúa, was not enough, too mired in an opposition defined by the oppressor. 'Th[at] counterstance, ' she wrote, is 'a step towards liberation from cultural domination. But it is not a way of life' (Anzaldúa 2007, 78). Instead, she turned attention to the unpredictable, emergent possibilities that take shape in the borderlands, born out of an embrace of ambiguity. For Anzaldúa, it is precisely the state of being caught between worlds that creates the conditions of possibility for alternative ways of seeing, knowing, and existing. Although hers was a heavily psychologised rendering, subsequent developments by feminist scholars have further filled in the social and political potential of the borderlands concept (Icaza 2020; Lugones 1992). Feminist philosopher Maria Lugones offers a particularly rich extension of Anzaldúa's writing, highlighting how acts of resistance from the borderlands, if seen as processual, become parts of a greater collective movement for change. It is thus both Alzaldua's theory of the borderlands, and the conversations it has provoked, that provides the conceptual orientation for this special issue of Sites.When the four of us gathered in May of 2019 to coordinate that year's Somaa (Society of Medical Anthropology of Aotearoa) symposium, we sought a theme that could explore the porosity of bodies -biological, institutional, geographic, and otherwise -and engage with their unsettled, transitional nature. Anzaldúa's