The bone Gla protein osteocalcin is expressed in cranial neural crest cells
Rotem Kalev-Altman,
Veatriki Fraggi-Rankis,
Efrat Monsonego-Ornan
et al.
Abstract:Background
Osteocalcin is a small protein abundant in the bone extracellular-matrix, that serves as a marker for mature osteoblasts. To become activated, osteocalcin undergoes a specific post-translational carboxylation. Osteocalcin is expressed at advanced stages of embryogenesis and after birth, when bone formation takes place. Neural crest cells (NCCs) are a unique cell population that evolves during early stages of development. While initially NCCs populate the dorsal neural-tube, later they u… Show more
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