The Boron Nitride Nanotube, an Ideal Host Structure for Efficient Immobilization and Delivery of RNA Aptamer: Classical Molecular Dynamics Simulation

Growth methodologies of boron nitride nanotubes and their neutron shielding applications: a review

“…The lightweight yet robust nature of BNNTs, combined with their high neutron attenuation efficiency, make them ideal candidates for protecting spacecraft and astronauts from cosmic radiation. 68,69 Additionally, the potential of BNNTs in medical applications, 22,[70][71][72][73][74][75][76][77][78] particularly in Boron Neutron Capture Therapy (BNCT), for cancer treatment was explored. 70,[79][80][81][82] BNCT leverages the high neutron capture cross-section of boron-10 (3835 barns 26 ) in BNNTs to selectively target and destroy cancer cells, thereby presenting a novel approach in oncology.…”

Boron nitride nanotube scaffolds: emergence of a new era in regenerative medicine

“…Computational studies to understand drug-BNNT interactions have also been documented using a wide range of small molecule therapeutic agents such as efavirenz, an antiretroviral drug [119], isoniazid, an antibacterial compound [120], paracetamol, an antipyretic molecule [121], leflunomide, an immunosuppressant [122], propylthiouracil, an anti-thyroid [123], pyrazinamide, an anti-tuberculosis agent [124] and chitosan [125]. It was found from the MD simulation that the BNNTs can also be used for delivering RNA aptamer [126], vitamin B3, vitamin C [127].…”

Improved delivery and competitive adsorption of paclitaxel and mitomycin C anticancer drugs on boron nitride nanoparticles: a molecular dynamics insight

“…12–14 Recently, scientists have reported excellent nontoxicity and biocompatibility for boron nitride nanotubes and nanosheets. 15–19 A molecular dynamics simulation on boron nitride nanosheet interaction with the membranes of cells was performed by Hilder et al 20 Additionally, Mateti et al 21 examined the possible biological applications of BNNSs. They suggested that the size and structure of the nanosheet changes the BNNS biocompatibility.…”