The Brain in the Skin: Neuro-Epidermal Synapses

Boulais, Nicholas; Miséry, Laurent

doi:10.1007/978-1-84882-322-8_3

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2013

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“…In nature tactile sensing is based on mechanotransduction, the mechanism by which cells convert mechanical stimuli into biological and biochemical signals, involving specialized mechanoreceptors [1,2]. Mechanical stimulation alters cellular membrane structure inducing conformational changes in stress-sensitive ion channels, thus leading to a variation in their opening/closing rates.…”

Section: Introductionmentioning

confidence: 99%

Soft, Stretchable and Conductive Biointerfaces for Bio-hybrid Tactile Sensing Investigation

Bernardeschi

Greco

Ciofani

et al. 2013

Biomimetic and Biohybrid Systems

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Abstract. In this work we present the design, fabrication and characterization of polymer-based soft, stretchable and conductive biointerfaces for achieving both mechanical stimulation of cells and recording of their response. These biointerfaces represent the very first step for investigating potential bio-hybrid tactile sensing approaches. Cells transform mechanical stimuli into biological and biochemical signals (mechanotransduction): modifications on cell membrane structure lead to a final change in membrane electric potential. Therefore, an efficient way to quantify cellular response to mechanical stimuli is to evaluate the impedance variation of cells due to externally applied forces.

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Section: Introductionmentioning

confidence: 99%