The burden of cancer at work: estimation as the first step to prevention

Rushton, Lesley; Hutchings, Sally; Brown, Terry

doi:10.1136/oem.2007.037002

Cited by 109 publications

(87 citation statements)

References 76 publications

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“…In a study conducted in Great Britain, it was calculated that, in 2004, approximately 7,300 deaths would be attributable to cases of occupational cancer, in contrast with the statistical records of 223 deaths from occupational diseases in the same year. (8) In Brazil, data on cancer and occupation are scarce. One study involving 316 cases and 536 controls at 14 hospitals in the city of São Paulo, Brazil, calculated that the risk of cancer doubled (OR = 1.97; 95% CI: 1.52-2.55) when groups at higher and lower risk of exposure to carcinogens were compared.…”

Section: Classification Of Carcinogenic Agentsmentioning

confidence: 99%

“…(6) Exposure to asbestos, alone, is estimated to be responsible for at least half of the cases of lung cancer attributable to occupation. (7,8) Recently, the Brazilian National Ministry of Health issued a decree making it mandatory that cases of occupational lung cancer be reported. (9) The Social Security Regulation-Decree 3048/99, amended by Decree no.…”

Section: Occupational Agents Related To Lung Cancermentioning

confidence: 99%

“…(6) In two recent studies, the PAR was calculated to be 11.6% and 4.9%, respectively. (8,16) In an estimate made in the USA and derived from relative risks described in the literature, PAR was calculated to be 9%. (7) Although the fraction of workers exposed to occupational carcinogens in developing countries might be similar to that found in developed countries, it should be borne in mind that the exposure conditions are much worse in the former.…”

Section: Occupational Burden Of Lung Cancermentioning

confidence: 99%

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Câncer de pulmão ocupacional

2010

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The principal risk factor for lung cancer is smoking, which is largely responsible for the development of the disease in men and women. It is estimated that 10-15% of all deaths from lung cancer in the USA are caused by risk factors other than smoking. In isolation, these would account for 16,000-24,000 deaths per year, which would still place lung cancer among the ten most deadly forms of cancer.(3) Occupational carcinogens can act alone or in synergy with smoking. A review of lung cancer in Brazil discussed the principal risk factors, notably smoking, and the economic sectors where carcinogens are strongly present. The economic sectors listed included IntroductionCarcinogens are often found in the workplace. Until the 1970s, most of the known human carcinogens were encountered in the workplace. The work environment remains a significant source of carcinogens.( 1) Carcinogenesis is a multifactorial process in which there is interaction among hereditary, genetic, and environmental factors that lead to uncontrolled cell growth. From this standpoint, occupational cancer is not considered a typical occupational disease, but rather a disease in which work, as an environmental factor, plays a decisive pathogenic role, by Schilling's criteria, which will be discussed below. AbstractLung cancer is a multifactorial disease. Hereditary, genetic, and environmental factors interact in its genesis. The principal risk factor for lung cancer is smoking. However, the workplace provides an environment in which there is a risk of exposure to carcinogens. The International Agency for Research on Cancer currently lists 19 substances/work situations/occupations that have been proven to be associated with lung cancer (group 1). Thorough occupational history taking is not widely practiced in patients with lung cancer, which has a negative impact on the investigation of causality and, consequently, on the identification of cases of occupational cancer. The objectives of this review were to list the agents that are recognized as causes of lung cancer, to discuss the contribution of occupation to the development of the disease, to cite national studies on the subject, and to propose a list of procedures that are essential to the appropriate investigation of causality between lung cancer and occupation.Keywords: Lung neoplasms; Occupational diseases; Occupations; Carcinogens. ResumoO câncer de pulmão é multicausal. Fatores hereditários, genéticos e ambientais interagem na sua gênese. O principal fator de risco é o tabagismo. Entretanto, o ambiente de trabalho é um local de possível exposição a agentes cancerígenos. Atualmente, a International Agency for Research on Cancer lista 19 substâncias/situações de trabalho/ocupações comprovadamente associadas ao câncer de pulmão (grupo 1). A abordagem da ocupação em pacientes portadores de câncer de pulmão é fraca, impactando negativamente na busca da causalidade e, consequentemente, no desvelamento de casos de câncer ocupacional. Os objetivos desta revisão foram elencar os agentes reconhecidame...

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Section: Classification Of Carcinogenic Agentsmentioning

confidence: 99%

Section: Occupational Agents Related To Lung Cancermentioning

confidence: 99%

Section: Occupational Burden Of Lung Cancermentioning

confidence: 99%

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Câncer de pulmão ocupacional

2010

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“…По данным Всемирной организации здравоохране-ния (ВОЗ, 2007) ежегодно, как минимум, 200 000 человек умирают от рака, связанного с условиями, в которых они работают [4].…”

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Current aspects of occupational oncopathology

Starinsky¹,

Sosnovskaya²,

Грецова³

et al. 2014

Onkol. Z. im. P.A. Gercena

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Ключевые слова : профессиональный рак, онкология, злокачественные новообразования, заболеваемость, смертность, профилактика, профессиональные заболевания. occupational cancer is considered to be one of the most complex problems in occupational diseases. the contribution of professional exposures into the cause of death from different locations of malignant neoplasms varies from 1% (prostate) to 25% (lung, nasal sinuses, etc.). According to the estimates of the international labor organization, cancers are the most common cause of death, which is associated with working conditions and far ahead of the statistics of deaths from industrial accidents and other occupational diseases. Almost one third of all work-related deaths are caused by cancer.

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“…Metal exposure from fumes during hyperbaric welding is a potential source of carcinogens [4,5]. Thus, high cancer rates have been observed in construction and metal workers [6]. As divers do welding in both wet and dry compartments, they may be at excess risk of developing cancer [7].…”

Section: Introductionmentioning

confidence: 99%