2022
DOI: 10.3390/nu14183809
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The Burden of Carbohydrates in Health and Disease

Abstract: Foods high in carbohydrates are an important part of a healthy diet, since they provide the body with glucose to support bodily functions and physical activity. However, the abusive consumption of refined, simple, and low-quality carbohydrates has a direct implication on the physical and mental pathophysiology. Then, carbohydrate consumption is postulated as a crucial factor in the development of the main Western diseases of the 21st century. We conducted this narrative critical review using MedLine (Pubmed), … Show more

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Cited by 89 publications
(78 citation statements)
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References 262 publications
(296 reference statements)
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“…This adaptation is achieved by reducing the levels of in ammatory mediators and oxidative stress. The effects of antioxidants on recovery and sports performance have also been well evaluated in the above study (32). Blueberries are often considered to have one of the highest antioxidant contents among fruits.…”
Section: Discussionmentioning
confidence: 97%
“…This adaptation is achieved by reducing the levels of in ammatory mediators and oxidative stress. The effects of antioxidants on recovery and sports performance have also been well evaluated in the above study (32). Blueberries are often considered to have one of the highest antioxidant contents among fruits.…”
Section: Discussionmentioning
confidence: 97%
“…The mechanism leading to carbohydrates toxicity is through the high concentration of fructose, glucose, advanced glycation end products (AGEs) (as a result of dihydroxyacetone phosphate and methylglyoxal). Moreover, there is need for the body to import essential amino acids, vitamins, minerals and other vital nutrients (Kroemer et al, 2018;Clemente-suarez et al, 2022).…”
Section: Discussionmentioning
confidence: 99%
“…Several environmental and lifestyle factors, such as smoking and alcohol consumption, have been associated with cancer development, including GI cancer [ 16 ]. Nevertheless, growing consensus also positions dietary habits as relevant risk factors for GI cancers [ 17 , 18 , 19 ]. Current evidence suggests that socioeconomic development results in several lifestyle modifications, including shifts in dietary habits to potentially less-healthy diets [ 14 , 20 , 21 , 22 ].…”
Section: Introductionmentioning
confidence: 99%