The burden of carotid artery plaques is higher in patients with psoriatic arthritis compared with those with psoriasis alone

Abstract

PsA patients suffer from more severe subclinical atherosclerosis compared with patients with PsC. This difference is independent of traditional cardiovascular risk factors and correlates with PsA disease duration, more severe skin disease and increased inflammatory markers.

Increased risk of arrhythmia in patients with psoriatic disease: A nationwide population-based matched cohort study

“…Our study showed that the risk for cardiac arrhythmia is higher in patients with psoriasis than in the general population, even after adjustment, suggesting the involvement of J AM ACAD DERMATOL VOLUME jj, NUMBER j other factors intrinsically linked to psoriasis and independent of the development of structural heart diseases (eg, heart failure and ischemic heart disease). Moreover, PsA, which includes inflammation of skin and joints, [20][21][22] was associated with a greater risk of arrhythmia, further indicating that inflammation may be an important link between arrhythmia and psoriasis. Among various subtypes of arrhythmia, psoriasis carried the highest risk for paroxysmal supraventricular tachycardia.…”

Serum adipokines in patients with psoriatic arthritis and psoriasis alone and their correlation with disease activity

“…Some of the patients included in this study had carotid artery ultrasound and plaque area measured 18. An analysis of those who participated in both studies revealed a correlation between plaque area and HOMA-IR (data not shown).…”

Increased prevalence of coronary plaque in patients with psoriatic arthritis without prior diagnosis of coronary artery disease

“…In addition, we were unable to precisely quantify lifetime dosages of medications to examine more fully the effect of pharmacologic therapy on the development of atherosclerosis. Third, as patients with PsA suffer from more severe subclinical carotid atherosclerosis compared with patients with psoriasis (PsO),40 it would be interesting to include patients with PsO to address whether this is also true for coronary atherosclerosis. Fourth, disease activity in these patients with PsA was low to moderate.…”