The Burden of Moderate to Severe Atopic Dermatitis in Canadian Children: A Cross-Sectional Survey

Bridgman, Alanna C.; Eshtiaghi, Panteha; Cresswell-Melville, Amanda; Ramien, Michele; Drucker, Aaron M.

doi:10.1177/1203475418761859

Cited by 28 publications

(37 citation statements)

References 4 publications

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“…The results of our and other [30][31] studies indicate a dynamic increase in the prevalence of AD. In our studies, we confirmed the recommendations [32] to grade the severity of AD, while agreeing that the best tool for assessing clinical signs of AD is the SCORAD scale.…”

Section: Discussionsupporting

confidence: 76%

Serum thymus and activation-regulated chemokinelevels in children with atopic dermatitis

Sorokman¹,

Sokolnyk²,

Sokolnyk³

et al. 2019

Ro J Pediatr.

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Section: Discussionsupporting

confidence: 76%

Serum thymus and activation-regulated chemokinelevels in children with atopic dermatitis

Sorokman¹,

Sokolnyk²,

Sokolnyk³

et al. 2019

Ro J Pediatr.

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“…Some sleep deprivation is expected for all parents of young infants, but childhood AD worsens this issue considerably. Sleep disruption is well known to occur in patients with AD, so it is unsurprising that their parents’ sleep is also diminished . The sleep loss in some parents of AD patients can be comparable in severity to that experienced by parents of children with various other chronic conditions, including autism spectrum disorder, mental retardation, and seizure disorders .…”

Section: Methodsmentioning

confidence: 99%

“…Sleep disruption is well known to occur in patients with AD, 2 so it is unsurprising that their parents' sleep is also diminished. 6 The sleep loss in some parents of AD patients can be comparable in severity to that experienced by parents of children with various other chronic conditions, including autism spectrum disorder, mental retardation, and seizure disorders. 23 In a survey study of parents of 203 infants attending pediatric dermatology clinics for AD, caregivers reported that the greatest impact that AD had on their own lives is sleep loss and tiredness.…”

Section: Parental Sleep Disturbancementioning

confidence: 98%

“…The effects of AD can extend well beyond affected children and diminish their families' quality of life (QoL) as well. 5,6 Increased severity of AD, both perceived by the caregiver 7 and by physicians, 8 is correlated with greater reduction in family QoL, while treatment of AD has been shown to improve family QoL. 9 Effective treatment and recognition of factors causing impaired QoL are important for physicians to understand as they attempt to reduce the negative impact of AD.…”

mentioning

confidence: 99%

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The impact of pediatric atopic dermatitis on families: A review

Yang

Beck

Sekhon

et al. 2018

Pediatric Dermatology

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Background Atopic dermatitis (AD) is an extremely common childhood disease, with considerable impact on the quality of life of affected children and their families. While pruritus is the hallmark symptom of this disease, AD has been well‐documented to impact patients beyond physical symptoms, resulting in behavior problems, mood disorders, and sleep disturbance. Objective This literature review outlines how atopic dermatitis impacts the quality of life of families of children affected by AD. Methods A total of 3436 articles were identified via an online search of the MEDLINE health literature database and were screened for relevance to quality of life impacts on families with children affected by AD. Results Caring for children affected by AD can be an extremely time‐consuming task that can impair personal relationships, decrease psychosocial functioning, and cause sleep loss among family members of affected patients. Additionally, AD may result in work absence or decreased work productivity for caregivers. Special diets, irritant and allergen avoidance strategies, and alternative therapies are commonly used by patients to manage their disease and require large amounts of family involvement. Conclusions Atopic dermatitis can greatly decrease quality of life of families of affected children in various domains, including sleep, finances, and relationships. Early intervention and psychotherapy may be needed in some patients to address these quality of life impairments.

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“…While mortality from skin disease is rare, many skin diseases are chronic and associated with substantial morbidity. [1][2][3][4] There are estimates of incidence and prevalence of specific diseases such as psoriasis, atopic dermatitis, and melanoma, but to date, there has been no comprehensive study of the burden of skin diseases and their associated disability in Canada. [5][6][7] The Global Burden of Disease (GBD) study aims to provide estimates of the fatal and nonfatal burden of disease.…”

Section: Introductionmentioning

confidence: 99%

Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study

et al. 2020

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Background Skin diseases can have high morbidity that can be costly to society and individuals. To date, there has been no comprehensive assessment of the burden of skin disease in Canada. Objectives To evaluate the burden of 18 skin and subcutaneous diseases from 1990 to 2017 in Canada using the Global Burden of Disease (GBD) data. Methods The 2017 GBD study measures health loss from 359 diseases and injuries in 195 countries; we evaluated trends in population health in Canada from 1990 to 2017 using incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs). Data are presented as rates (per 100 000), counts, or percent change with the uncertainty interval in brackets. Results From 1990 to 2017 for all skin diseases, DALY rates increased by 8% to 971 per 100 000 (674-1319), YLD rates increased by 8% to 897 per 100 000 (616-1235), YLL rates increased by 4% to 74 per 100 000 (53-89), and death rates increased by 18% to 5 per 100 000 (3-6). DALY rates for melanoma increased by 2% to 54 per 100 000 (39-68), for keratinocyte carcinoma by 14% to 17 per 100 000 (16-19), and for skin and subcutaneous disease by 8% to 900 per 100 000 (619-1233). The observed over expected ratios were higher for skin and subcutaneous disease (1.37) and keratinocyte carcinoma (1.17) and were lower for melanoma (0.73). Conclusions The burden of skin disease has increased in Canada since 1990. These results can be used to guide health policy regarding skin disease in Canada.

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The Burden of Moderate to Severe Atopic Dermatitis in Canadian Children: A Cross-Sectional Survey

Cited by 28 publications

References 4 publications

Serum thymus and activation-regulated chemokinelevels in children with atopic dermatitis

Serum thymus and activation-regulated chemokinelevels in children with atopic dermatitis

The impact of pediatric atopic dermatitis on families: A review

Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study

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