The burden of segregated respiratory diseases in India and the quality of care in these patients: Results from the Asia-Pacific Burden of Respiratory Diseases study

Ghoshal, Aloke Gopal; Ravindran, G D; Gangwal, P; Rajadhyaksha, Girish; Cho, Sang Heon; Muttalif, Abdul Razak; Lin, Horng‐Chyuan; Thanaviratananich, Sanguansak; Bagga, Shalini; Faruqi, Rab; Sajjan, Shiva; Shetty, Pradeep Nanjappa; Syed, Raeesuddin; Hamrosi, Kim K; Wang, De Yun

doi:10.4103/0970-2113.192878

Cited by 25 publications

(29 citation statements)

References 25 publications

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“…Some of the country-specific findings have been reported for India, Korea, Taiwan, and Thailand [13-16]. Here we report additional country-specific findings as well as the results differentiated between general practitioners (GP) and specialists regarding country-specific practice patterns, patient characteristics, HCRU, and health-related QoL for patients with a primary diagnosis of AR, asthma, COPD, or rhinosinusitis.…”

Section: Introductionmentioning

confidence: 52%

Practice Patterns for Chronic Respiratory Diseases in the Asia-Pacific Region: A Cross-Sectional Observational Study

Wang

Cho

Lin

et al. 2018

Int Arch Allergy Immunol

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Background: Allergic rhinitis (AR), asthma, chronic obstructive pulmonary disease (COPD), and rhinosinusitis are common and little studied in the Asia-Pacific region. Objectives: We sought to investigate real-world practice patterns for these respiratory diseases in India, Korea, Malaysia, Singapore, Taiwan, and Thailand. Methods: This cross-sectional observational study enrolled adults (age ≥18 years) presenting to general practitioners (GP) or specialists for physician-diagnosed AR, asthma, COPD, or rhinosinusitis. Physicians and patients completed study-specific surveys at one visit, recording patient characteristics, health-related quality of life (QoL), work impairment, and healthcare resource use. Findings by country and physician category (GP or specialist) were summarized. Results: Of the 13,902 patients screened, 7,243 (52%) presented with AR (18%), asthma (18%), COPD (7%), or rhinosinusitis (9%); 5,250 of the 7,243 (72%) patients were eligible for this study. Most eligible patients (70–100%) in India, Korea, Malaysia, and Singapore attended GP, while most (83–85%) in Taiwan and Thailand attended specialists. From 42% (rhinosinusitis) to 67% (AR) of new diagnoses were made by GP. On average, patients with COPD reported the worst health-related QoL, particularly to GP. Median losses of work productivity for each condition and activity impairment, except for asthma, were numerically greater for patients presenting to GP vs. specialists. GP prescribed more antibiotics for AR and asthma, and fewer intranasal corticosteroids for AR, than specialists (p < 0.001 for all comparisons). Conclusions: Our findings, albeit mostly descriptive and influenced by between-country differences, suggest that practice patterns differ between physician types, and the disease burden may be substantial for patients presenting in general practice.

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Section: Introductionmentioning

confidence: 52%

Practice Patterns for Chronic Respiratory Diseases in the Asia-Pacific Region: A Cross-Sectional Observational Study

Wang

Cho

Lin

et al. 2018

Int Arch Allergy Immunol

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“…8,12 Present study revealed that chronic cough and phlegm was significantly higher among current and ex-smokers compared to non-smokers. 4,8,9,11,13,14 Cigarette smoke contains thousands of chemical components, which can irritate and activate macrophages and cells that make up the lining of the airways (epithelial cells). This causes the cells to release multiple types of cytokines, which are small signaling proteins that cause the airway lining to thicken and airways to become inflamed.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of chronic respiratory symptoms in an urban population of North Kerala

Vasudevan

Silpa

2019

Int J Community Med Public Health

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INTRODUCTIONWith the advent of antibiotics in 1940s, the importance of acute respiratory tract infection as a cause of high mortality and morbidity, declined rapidly in developed countries and also it is decreasing in developing countries. However the burden of chronic diseases of respiratory system is increasing day by day. Tobacco smoking, socio economic development, urbanization, associated life style changes and resulting increase in air pollution are undoubtedly the underlying causative factors. Apart from the discomfort of the symptoms and the prolonged treatment, chronic respiratory diseases are associated with a variety of serious complications, which result in high treatment costs, reduced quality of life, reduced productivity, and shortened life expectancy. ABSTRACTBackground: Chronic respiratory diseases are becoming a challenge to public health due to its high morbidity and mortality. Most of these diseases are preceded by variable periods of chronic respiratory symptoms. If chronic respiratory symptoms can be diagnosed and managed properly and timely, we can reduce the incidence and complication of chronic respiratory diseases. Methods: A community based cross sectional survey was conducted in 20 electoral wards of Calicut corporation of Northern Kerala among the adult resident population of 20-70 years to assess the prevalence of chronic respiratory symptoms such as chronic cough, phlegm, wheezing, breathlessness and nasal allergy and the factors associated with these chronic symptoms. The information was collected from 1384 eligible subjects selected by cluster sampling using British research council respiratory questionnaire. Results: About 9.2% (n=95) of study population had at-least one of the chronic respiratory symptoms. 1.8% (n=19) had all the chronic respiratory symptoms. Prevalence of various chronic respiratory symptoms was chronic cough (8.7%), Phlegm (14.3%), wheezing (8.5%), breathlessness (2.2%) and nasal allergy (14.5%). Advancing age, current smoking, family history and past history of various respiratory diseases are significantly associated with the development of chronic respiratory symptoms. Female gender, longer duration of stay in Calicut corporation and regular alcoholism were significantly associated with chronic phlegm in the study population. Wheezing, breathlessness and chronic nasal allergy was significantly higher among lower socio economic status. Conclusions: Prevalence of chronic respiratory symptoms is high among the urban population of Northern Kerala. Older age group, smoking, past and family history of respiratory diseases are the major risk factors associated with these respiratory symptoms.

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“…Understanding the socioeconomic burden on healthcare resources arising from these respiratory diseases is essential to identify effective interventions, plan priorities, and strategically allocate funds and resources to reduce the burden of these respiratory diseases in India. While several studies have addressed prevalence, diagnosis, and treatment of the above respiratory diseases in India, no studies to date have explored the burden of care in adults who present to healthcare professionals (HCP) using one standard protocol 5 . Respiratory diseases constitute a major cause of morbidity and mortality worldwide, the top five respiratory diseases accounting for 17.4% of all deaths and 13.3% of all disability-adjusted life years in the year 2000 6 .…”

Section: Introductionmentioning

confidence: 99%

A Retrospective Study on Drug Utilization Review and Prescribing Pattern in Patients With Respiratory Diseases in a Tertiary Care Hospital, Salem, India

Afarath¹,

Varghese²,

Wilson³

et al. 2019

Int. Res. J. Pharm.

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A retrospective study was conducted on 450 cases, to study the drug utilization review and prescribing pattern in patients with respiratory diseases in a tertiary care hospital. Among 450 cases majority of the cases were COPD (30.9%). Nebulizer was the preferred dosage form for BA (36%), COPD (38%) and Bronchitis (39%), injections for LRTI (30%), syrups for URTI (37%) and capsules for Pharyngitis (62%).46 prescriptions were found to have drug-drug interactions, Dexamethasone + Theophylline and Dexamethasone+ Budesonide were found to have 28.26% of interactions. B2 adrenergic receptor agonist was most commonly prescribed class of drug for BA (31%), COPD (32%), LRTI (35%), URTI (39%) and Bronchitis (43%) where in the cases of Pharyngitis, Antihistamines (82%). In BA (31%), COPD(67%), LRTI(45%) and Bronchitis(50%), Ceftriaxone was the preferred class of Antibiotics while Amoxicillin for URTI (80%) and Pharyngitis (68%). Out of 1472 prescribed drugs, 904(61%) drugs were prescribed in brand name and 568 (39%) drugs were prescribed in generic name, 61% of drugs were used as monotherapy while 39% of drugs were used as combination therapy. Asthalin (45%) was the most commonly prescribed drug according to Essential Drug List. From the study, it is concluded that the doctors were aware about the use of drugs, safety of prescribing drugs from Essential Drug List (EDL) but there was a lack of knowledge on prescribing with generic names. In the present study most patients were on monotherapy but Patients with respiratory diseases mostly require more than one drug to control the symptoms.

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The burden of segregated respiratory diseases in India and the quality of care in these patients: Results from the Asia-Pacific Burden of Respiratory Diseases study

Cited by 25 publications

References 25 publications

Practice Patterns for Chronic Respiratory Diseases in the Asia-Pacific Region: A Cross-Sectional Observational Study

Practice Patterns for Chronic Respiratory Diseases in the Asia-Pacific Region: A Cross-Sectional Observational Study

Prevalence of chronic respiratory symptoms in an urban population of North Kerala

A Retrospective Study on Drug Utilization Review and Prescribing Pattern in Patients With Respiratory Diseases in a Tertiary Care Hospital, Salem, India

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