The burden of tick-borne diseases in the Altai region of Russia

Dedkov, Vladimir G.; Симонова, Е. Г.; Beshlebova, Olga; Safonova, Marina V.; Стуколова, О. А.; Веригина, Е. В.; Savinov, G.V.; Karaseva, I.P.; Blinova, Ekaterina A.; Гранитов, В. М.; Arsenjeva, Irina; Shipulin, German A.

doi:10.1016/j.ttbdis.2017.06.004

Cited by 19 publications

(12 citation statements)

References 10 publications

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“…Human granulocytic anaplasmosis (HGA) is a tickborne intracellular bacterial infection caused by Anaplasma phagocytophilum . The disease is present in North America, Europe, and northern Asia, areas with Ixodes ricinus ticks, the primary vector for transmission to humans ( 1 , 2 ). Clinical manifestations of disease include acute fever, headache, and myalgia occurring 2–3 weeks after tick bite.…”

mentioning

confidence: 99%

Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France

Hansmann¹,

Jaulhac²,

Kieffer³

et al. 2019

Emerg. Infect. Dis.

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mentioning

confidence: 99%

Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France

Hansmann¹,

Jaulhac²,

Kieffer³

et al. 2019

Emerg. Infect. Dis.

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“…By using cell cultures, rickettsiae can be detected 48 to 72 h after inoculation by the infected tick. This technique is crucial for identifying new species enabling genetic descriptions, physiological On the right-the state of knowledge in 2019 [1,4,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31]33,35,36,38,39,[41][42][43][44][45][46][47]56,.…”

Section: Diagnosticsmentioning

confidence: 99%

“…The occurrence of pathogenic tick-borne species belonging to the genus Rickettsia in the world at the beginning of the 21st century compared to now. On the left-the state of knowledge in 2005.On the right-the state of knowledge in 2019[1,4,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31]33,35,36,38,39,[41][42][43][44][45][46][47]56,.…”

mentioning

confidence: 99%

Expansion of Tick-Borne Rickettsioses in the World

Piotrowski

Rymaszewska

2020

Microorganisms

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Tick-borne rickettsioses are caused by obligate intracellular bacteria belonging to the spotted fever group of the genus Rickettsia. These infections are among the oldest known diseases transmitted by vectors. In the last three decades there has been a rapid increase in the recognition of this disease complex. This unusual expansion of information was mainly caused by the development of molecular diagnostic techniques that have facilitated the identification of new and previously recognized rickettsiae. A lot of currently known bacteria of the genus Rickettsia have been considered nonpathogenic for years, and moreover, many new species have been identified with unknown pathogenicity. The genus Rickettsia is distributed all over the world. Many Rickettsia species are present on several continents. The geographical distribution of rickettsiae is related to their vectors. New cases of rickettsioses and new locations, where the presence of these bacteria is recognized, are still being identified. The variety and rapid evolution of the distribution and density of ticks and diseases which they transmit shows us the scale of the problem. This review article presents a comparison of the current understanding of the geographic distribution of pathogenic Rickettsia species to that of the beginning of the century.

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“…Moreover, these high-throughput screenings of TBPs in individual ticks have highlighted the co-occurrence of several pathogens in one tick, known as tick coinfections. Before the use of this novel technique, tick coinfections were evaluated by classical PCR, nested PCR or real-time PCR, and related publications focused in few pathogens, less than 10 different genera screened per publication [43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59]. After the year 2016, two publications have demonstrated the presence of up to five and four different pathogen species in I. ricinus female ticks collected in France and Romania, respectively, using this high-throughput system [9,20].…”

Section: Tick-borne Pathogen Coinfections Revealed By Microfluidic Pcrmentioning

confidence: 99%

“…Unfortunately, only few publications are available regarding coinfection by bacteria and parasites or bacteria and viruses or parasites and viruses in ticks [49,50,52,54,60]. To solve this gap of information regarding inter-taxa coinfections, a system to detect simultaneously bacteria, parasites and viruses will be, without any doubt, an improvement of available tools.…”

Section: Challenges and Perspectivesmentioning

confidence: 99%

Handling the Microbial Complexity Associated to Ticks

Cabezas‐Cruz¹,

Pollet²,

Estrada-Peña³

et al. 2019

Ticks and Tick-Borne Pathogens

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Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. In the last years, high-throughput detection and sequencing technologies (HTT) have revealed that individual ticks carry a high diversity of microorganisms, including pathogenic and non-pathogenic bacteria. Despite several studies have contributed to the availability of a catalog of microorganisms associated to different tick species, major limitations and challenges remain ahead HTT studies to acquire further insights on the microbial complexity associated to ticks. Currently, using next generation sequencing (NGS), bacteria genera (or higher taxonomic levels) can be recorded; however, species identification remains problematic which in turn affects pathogen detection using NGS. Microfluidic PCR, a high-throughput detection technology, can detect up to 96 different pathogen species, and its combination with NGS might render interesting insights into pathogenmicrobiota co-occurrence patterns. Microfluidic PCR, however, is also limited because detection of pathogen strains has not been implemented, and therefore, putative associations among bacterial genotypes are currently unknown. Combining NGS and microfluidic PCR data may prove challenging. Here, we review the impact of some HTT applied to tick microbiology research and propose network analysis as an integrative data analysis benchmark to unravel the structure and significance of microbial communities associated to ticks in different ecosystems.

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The burden of tick-borne diseases in the Altai region of Russia

Cited by 19 publications

References 10 publications

Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France

Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France

Expansion of Tick-Borne Rickettsioses in the World

Handling the Microbial Complexity Associated to Ticks

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