“…1,12,34,35,[38][39][40][41][42][43] These studies involved a total of 614 RRP patients (all sampled from outpatient departments) receiving 2120 laser surgeries, including 102 KTP cases and 512 CO 2 cases. There were eight retrospective studies 1,12,34,35,[38][39][40]42 with only two prospective works 41,43 in the CO 2 group, whereas the KTP group contained two retrospective 10,44 and three prospective studies. 29,36,37 Furthermore, the patient populations differed by study, with most studies recruiting patients having recurrent laryngeal/respiratory papillomatosis, whereas others included inverted papilloma, 29 laryngeal papilloma, 1,34,40,44 or juvenile-onset RRP (Table 1).…”