The Cache County Study on Memory in Aging: Factors affecting risk of Alzheimer's disease and its progression after onset

Abstract

The Cache County Study on Memory in Aging is a longitudinal, population-based study of Alzheimer's disease (AD) and other dementias. Initiated in 1995 and extending to 2013, the study has followed over 5,000 elderly residents of Cache County, Utah (USA) for over twelve years. Achieving a 90% participation rate at enrollment, and spawning two ancillary projects, the study has contributed to the literature on genetic, psychosocial and environmental risk factors for AD, late life cognitive decline, and the clinical progression of dementia after its onset. This paper describes the major study contributions to the literature on AD and dementia.

Digital technologies for the assessment of cognition: a clinical review

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“…Cognitive scores were higher, both at baseline and subsequently, for those consuming ready-to-eat (RTE) cereals more frequently than weekly but less frequently than daily. Daily and nonconsumers of RTE cereals had lower scores (78). In the Women's Health Study, higher whole grain intake (2.2 servings/day) was associated with higher average cognition scores compared with women whose daily intake of whole grains was lower (0.8 servings/day) (79).…”

“…The study showed that consumption of excess amounts of grain and white bread products and inadequate amounts of dietary fiber were problematic, underscoring the need for dietary balance (75). The benefits of dietary balance were also demonstrated in a study of 4,000 elderly adults in the 12 year Cache County (Utah) Study on Memory Health and Aging (78). Cognitive scores were higher, both at baseline and subsequently, for those consuming ready-to-eat (RTE) cereals more frequently than weekly but less frequently than daily.…”