2018
DOI: 10.1096/fasebj.2018.32.1_supplement.740.2
|View full text |Cite
|
Sign up to set email alerts
|

The caffeine effects on rotenone‐induced Parkinson's disease model in vitro and in vivo

Abstract: Introduction and hypothesisThe degeneration and lost on dopaminergic neurons in midbrain may cause Parkinson's disease, and it is one of the most common neurodegenerative disease in human. Rotenone is a natural lipophilic toxic compound that is easy to cross the blood‐brain barrier, and widely used as insecticide and pesticide. Rotenone may impair mitochondrial oxidative phosphorylation and lead to dopaminergic neuron loss. In this study we investigated the protective effects of caffeine on rotenone‐induced Pa… Show more

Help me understand this report

This publication either has no citations yet, or we are still processing them

Set email alert for when this publication receives citations?

See others like this or search for similar articles