We prove a unique continuation property for the fractional Laplacian (−∆) s when s ∈ (−n/2, ∞) \ Z where n ≥ 1. In addition, we study Poincaré-type inequalities for the operator (−∆) s when s ≥ 0. We apply the results to show that one can uniquely recover, up to a gauge, electric and magnetic potentials from the Dirichlet-to-Neumann map associated to the higher order fractional magnetic Schrödinger equation. We also study the higher order fractional Schrödinger equation with singular electric potential. In both cases, we obtain a Runge approximation property for the equation. Furthermore, we prove a uniqueness result for a partial data problem of the d-plane Radon transform in low regularity. Our work extends some recent results in inverse problems for more general operators.