The CAPTURE registry: Results of carotid stenting with embolic protection in the post approval setting

Abstract

The results of the CAPTURE study compare favorably to those achieved in the predicate pivotal investigations, and suggest that the post-approval transfer of this new therapy to the community practice setting via carotid stent training programs is effective in preparing physicians with varying experience levels and specialty training backgrounds.

2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: Executive summary

“…42,181,[187][188][189][190][191][192][193][194][195][196] The risk of arterial dissection or thrombosis in all published series was <1%. Target-vessel perforation occurred in <1% of cases, and external carotid artery stenosis or occlusion occurred in 5% to 10%, 42,53,181, but this event is typically benign, requiring no further intervention. The incidence of restenosis after CAS has been in the range of 3% to 5%.…”

“…[245][246][247][248][249][250][251] If properly deployed, an EPD can reduce the neurological risks associated with CAS, but these devices may also be associated with failures. 53,196,198,247,[252][253][254][255][256][257][258] Among the general risks is access-site injury, which complicates 5% of cases, but most such injuries involve pain and hematoma formation and are self-limited. [259][260][261][262] Contrast-induced nephropathy has been reported in <1% of cases, because CAS is generally avoided in patients with severe renal dysfunction.…”

Predictors and Timing of Hypotension and Bradycardia after Carotid Artery Stenting

“…19,20 Patients who had CAS to treat a nonatherosclerotic lesion, such as a carotid artery dissection or a pseudoaneurysm, were excluded.…”

The carotid artery revascularization and endarterectomy (CARE) registry: Objectives, design, and implications

“…CAS is a relatively new technology, with reports regarding the real-world implementation and outcomes associated with CAS now emerging [12]. There is a clear need to evaluate independently the frequency of use of CAS relative to CEA, and to characterize patient selection, procedural variances, and acute and 30-day outcomes in a contemporary registry.…”