“…Rates of obesity, smoking, angina, and respiratory symptoms are significantly higher than in the general population. 12 In the CATIE study, the 10-year risk of cardiovascular disease was significantly elevated in subjects treated for schizophrenia, compared with age-matched control subjects. Schizophrenia patients, compared with control subjects, had significantly higher rates of smoking (68% and 35%, respectively), diabetes (13% and 3%, respectively), and hypertension (27% and 17%, respectively), as well as lower HDL cholesterol levels (43.7 and 49.3 mg/dL, respectively) (P < 0.001).…”