The Cardiovascular Effects of Electronic Cigarettes

Khadka, Saroj; Awasthi, Manul; Lamichhane, Rabindra Raj; Ojha, Chandra; Mamudu, Hadii M.; Lavie, Carl J.; Paul, Timir K.

doi:10.1007/s11886-021-01469-4

Cited by 17 publications

(12 citation statements)

References 57 publications

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“…Similar to traditional combustible cigarettes, one study indicated that exposure to electronic cigarettes enhanced platelet activation and subsequently increased thrombogenesis ( 37 , 38 ). Additionally, the ultrafine particles in electronic cigarettes were also found to be associated with platelet activation ( 39 ). Third, a gradual increase in oxidative stress and inflammation was observed in acute electronic cigarette users, which is strongly associated with adverse cardiovascular events.…”

Section: Discussionmentioning

confidence: 99%

The association between electronic cigarettes, sleep duration, and the adverse cardiovascular outcomes: Findings from behavioral risk factor surveillance system, 2020

Liu

Yuan

2022

Front. Cardiovasc. Med.

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The joint effect of electronic cigarette smoking and insufficient sleep duration on cardiovascular disease (CVD) was unclear. This cross-sectional study aimed to evaluate the association between electronic cigarettes, sleep duration, and risk of CVD among American adults. The participants who completed the survey from the behavioral risk factor surveillance system in 2020 were included in this study. The status of electronic cigarette smoking was divided into never, former, and current use. The duration of sleep was categorized into insufficient (<6 h), appropriate (6–9 h), and excessive (>9 h) groups. The CVD group was defined as a patient having any of the following conditions: heart attack, coronary heart disease, or stroke according to self-report. The multivariate logistic regression model was adopted to determine the association between electronic cigarettes, sleep duration, and the risk of CVD. Sensitivity analyses were performed to assess the joint effects on the risk of CVD subtypes, including heart attack, coronary heart disease, and strokes, respectively. Subgroup analyses were performed to estimate the joint effects within the stratum of the age group. The total number of participants included in the present study was 253,561. Of which, 22,908 patients had CVD. In total, 61,293 participants had previously or currently used electronic cigarettes and 37,429 participants had inappropriate sleep duration. Former electronic cigarette users had a 10.8% increased risk of having CVD (OR = 1.108, 95% CI: 1.001–1.227) compared to users who never had electronic cigarettes. Insufficient and excessive sleep durations are associated with increased risks of CVD (OR = 1.592, 95% CI: 1.460–1.735; OR = 1.523, 95% CI: 1.320–1.758). The participants with current vaping status and lack of sleep had a 159.6% increased risk of CVD (OR = 2.596, 95% CI: 1.810–3.723). Sensitivity analyses found similar joint effects of current vaping and insufficient sleep on the risk of heart attack, coronary heart attack, and stroke. The subgroup analyses across each age stratum found that the middle-aged group is most vulnerable to the joint effect of current vaping and insufficient sleep. This study found that both current vaping and inappropriate sleep duration were associated with CVD. Additionally, there was a significant joint effect of current vaping and insufficient sleep on the risk of CVD, especially for middle-aged participants.

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Section: Discussionmentioning

confidence: 99%

The association between electronic cigarettes, sleep duration, and the adverse cardiovascular outcomes: Findings from behavioral risk factor surveillance system, 2020

Liu

Yuan

2022

Front. Cardiovasc. Med.

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“…Smoking in the setting of DM has been associated with significantly worse outcomes regarding cardiovascular mortality and morbidity, including CAD, stroke, peripheral vascular disease and HF. Considering that smoking is another standalone classic risk factor for CVD, its cessation is imperative in this high-risk population [ 73 ]. Regarding electronic cigarettes, data are scarce and raise significant concerns regarding their cardiovascular impact in people with or without diabetes mellitus.…”

Section: Lifestyle Interventionsmentioning

confidence: 99%

Cardiometabolic Care: Assessing Patients with Diabetes Mellitus with No Overt Cardiovascular Disease in the Light of Heart Failure Development Risk

et al. 2023

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The mechanisms leading to the development of heart failure (HF) in diabetes mellitus (DM) patients are multifactorial. Assessing the risk of HF development in patients with DM is valuable not only for the identification of a high-risk subgroup, but also equally important for defining low-risk subpopulations. Nowadays, DM and HF have been recognized as sharing similar metabolic pathways. Moreover, the clinical manifestation of HF can be independent of LVEF classification. Consequently, approaching HF should be through structural, hemodynamic and functional evaluation. Thus, both imaging parameters and biomarkers are important tools for the recognition of diabetic patients at risk of HF manifestation and HF phenotypes, and arrhythmogenic risk, and eventually for prognosis, aiming to improve patients’ outcomes utilizing drugs and non-pharmaceutical cardioprotective tools such as diet modification.

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“…How health will be affected in the long term hasn't yet been determined for all people who breathe aerosols. Also, it hasn't been determined by evidence, so far, that ENDS can serve in smoking cessation, as aids, since most of the e-cigarette users are dual users 15 . Negative consequences have also been added to the previous fact, since it has been shown that never smokers are more likely to start ENDS products by younger individuals, viewed as safe products 13 .…”

Section: World Health Organization (Who)mentioning

confidence: 99%

A Collection of Position Statements and Opinions on e-cigarette use and cardiovascular disease: On behalf of the Working Group on Epidemiology of the Hellenic Atherosclerosis Society

Notara¹,

Bobolou²,

Foscolou³

et al. 2022

JAPT

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There are accumulative evidences that the prevalence of cigarette smoking has gradually declined in most high-income countries since the 1990s, in part due to public health campaigns emphasizing on the relationship between tobacco use and detrimental health effects. In late 2000s electronic (e)-cigarettes were introduced in the world, as less harmful nicotine products that may also help people in quitting smoking. Since then, the use of e-cigarettes has increased rapidly from the time when their introduction in the global market. In this work we present a collection of position statements and opinions of scientific bodies and Organizations, regarding the safety of e-cigarettes, as well as their association with human health, and particularly, cardiovascular diseases.

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The Cardiovascular Effects of Electronic Cigarettes

Cited by 17 publications

References 57 publications

The association between electronic cigarettes, sleep duration, and the adverse cardiovascular outcomes: Findings from behavioral risk factor surveillance system, 2020

The association between electronic cigarettes, sleep duration, and the adverse cardiovascular outcomes: Findings from behavioral risk factor surveillance system, 2020

Cardiometabolic Care: Assessing Patients with Diabetes Mellitus with No Overt Cardiovascular Disease in the Light of Heart Failure Development Risk

A Collection of Position Statements and Opinions on e-cigarette use and cardiovascular disease: On behalf of the Working Group on Epidemiology of the Hellenic Atherosclerosis Society

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