1984
DOI: 10.1001/jama.1984.03350060051030
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The Cardiovascular Effects of Mechanical Ventilation and Positive End-Expiratory Pressure

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Cited by 94 publications
(18 citation statements)
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“…During LVR manoeuvres, mean P a decreased relative to baseline in both groups (figures 3 and 4), probably due to increases in intrathoracic pressure and reduced venous return [40]. The decrease in mean P a was greater in the controls than in those with RMW (figure 3), presumably due to the fact that controls tolerated higher inflation pressures (table 2).…”
Section: Discussionmentioning
confidence: 99%
“…During LVR manoeuvres, mean P a decreased relative to baseline in both groups (figures 3 and 4), probably due to increases in intrathoracic pressure and reduced venous return [40]. The decrease in mean P a was greater in the controls than in those with RMW (figure 3), presumably due to the fact that controls tolerated higher inflation pressures (table 2).…”
Section: Discussionmentioning
confidence: 99%
“…In contrast, with inadequate or absent PEEP, significant lung injury occurs with lower tidal volumes and distending pressures in a surfactant-depleted, isolated lung model (6). The protective effect of PEEP has been attributed primarily to prevention of repeated airway collapse and expansion (RACE) (6, 7), and to a lesser extent limitation of tidal excursion, and reduced cardiac output (8). …”
Section: Introductionmentioning
confidence: 99%
“…Our findings are supported by other investigations (6, 17, 18). The reduction of CO t during CPPV with less than 15 cm H 2 O has been attributed to a reduced venous return (2). One would expect that the reduced CO t due to a diminished SV would increase HR, but this was not the case.…”
Section: Discussionmentioning
confidence: 99%
“…C ONTINUOUS positive pressure ventilation (CPPV) depresses cardiac output (CO) (1, 2), and the main causal mechanism, decreased venous return, has long been well understood. It has also been established that the deterioration in CO is followed by an adjustment in its relative distribution (3, 4).…”
mentioning
confidence: 99%