The case for negative senescence

Vaupel, James W.; Baudisch, Annette; Dölling, Martin; Roach, Deborah A.; Gampe, Jutta

doi:10.1016/j.tpb.2003.12.003

Cited by 317 publications

(373 citation statements)

References 34 publications

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“…As Williams observed, however, "it is indeed remarkable that after a seemingly miraculous feat of morphogenesis a complex metazoan should be unable to perform the much simpler task of merely maintaining what is already formed" (Williams 1957: 398). Over the last decades, field and laboratory studies have demonstrated that some organisms suffer negligible senescence over the course of life (Finch 1990;2009;Vaupel et al 2004). Notable examples are queens in eusocial species (Hölldobler and Wilson 1990;Keller and Genoud 1997;Keller 1998;Carey 2001) and hydra (Martinez 1998).…”

Section: Introductionmentioning

confidence: 99%

Senescence vs. sustenance: Evolutionary-demographic models of aging

Baudisch¹,

Vaupel²

2010

DemRes

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Section: Introductionmentioning

confidence: 99%

Senescence vs. sustenance: Evolutionary-demographic models of aging

Baudisch¹,

Vaupel²

2010

DemRes

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“…This can change the strength of selection enough to promote prolonged somatic maintenance and reproduction, and allow the evolution of negligible senescence (Vaupel et al 2004;Baudisch 2005). Recent empirical work on organisms with indeterminate growth and fecundity suggests that increasing fecundity with advancing age may override decreasing survival with advancing age in these species, such that they may escape senescence altogether (Reznick et al 2004;Sparkman et al 2007).…”

Section: Introductionmentioning

confidence: 99%

The evolution of aging phenotypes in snakes: a review and synthesis with new data

Bronikowski

2008

AGE

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Reptiles are underutilized vertebrate models in the study of the evolution and persistence of senescence. Their unique physiology, indeterminate growth, and increasing fecundity across the adult female lifespan motivate the study of how physiology at the mechanistic level, life history at the organismal level, and natural selection at the evolutionary timescale define lifespan in this diverse taxonomic group. Reviewed here are, first, comparative results of cellular metabolic studies conducted across a range of colubrid snake species with variable lifespan. New results on the efficiency of DNA repair in these species are synthesized with the cellular studies. Second, detailed studies of the ecology, life history, and cellular physiology are reviewed for one colubrid species with either short or long lifespan (Thamnophis elegans). New results on the rate of telomere shortening with age in this species are synthesized with previous research. The comparative and intraspecific studies both yield results that species with longer lifespans have underlying cellular physiologies support the free-radical/repair mechanistic hypothesis for aging. As well, both underscore the importance of mortality environment for the evolution of aging rate.

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“…In human populations with high infant and childhood mortality but with such high fertility that the population is growing, the covariance can be negative. Furthermore, for many trees, fish and other non-human populations mortality tends to fall with age (Vaupel et al, 2004): for such species the death rate will rise when fertility rises.…”

Section: φ(A) = C(a)µ(a) C(a) = µ(A)mentioning

confidence: 99%