2021
DOI: 10.1111/1751-7915.13903
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The catalytic activity of mycelial fungi towards 7‐oxo‐DHEA – an endogenous derivative of steroidal hormone dehydroepiandrosterone

Abstract: Seventeen species of fungi belonging to thirteen genera were screened for the ability to carry out the transformation of 7-oxo-DHEA (7-oxodehydroepiandrosterone). Some strains expressed new patterns of catalytic activity towards the substrate, namely 16b-hydroxylation (Laetiporus sulphureus AM498), Baeyer-Villiger oxidation of ketone in D-ring to lactone (Fusicoccum amygdali AM258) and esterification of the 3b-hydroxy group (Spicaria divaricata AM423). The majority of examined strains were able to reduce the 1… Show more

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