2011
DOI: 10.1002/ajh.22158
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The cause of sudden anemia revealed by the blood film

Abstract: A three and a half-year-old girl of Indian ethnic origin presented with a 2-day history of fever and sore throat. She had also been passing red urine for the previous 24 hours. Her blood count showed: white cell count 27.5 x 10 9 /l, red cell count 2.76 x 10 12 /l, hemoglobin concentration 81 g/l, hematocrit 0.22 l/l, mean cell volume 80 fl, mean cell hemoglobin 29.6 pg, mean cell hemoglobin concentration (MCHC) 370 g/l. The increased MCHC suggested the presence of spherocytes, irregularly contracted cells or … Show more

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“…Peripheral blood smears frequently show polychromasia and spherocytosis. Autoagglutination is suggestive of cold agglutinin disease , while haemophagocytosis of RBCs by granulocytes is characteristic of PCH12 (figure 1A).…”
Section: Laboratory Findingsmentioning
confidence: 99%
“…Peripheral blood smears frequently show polychromasia and spherocytosis. Autoagglutination is suggestive of cold agglutinin disease , while haemophagocytosis of RBCs by granulocytes is characteristic of PCH12 (figure 1A).…”
Section: Laboratory Findingsmentioning
confidence: 99%