The Causes and Treatment of Dystocia in Beef Cattle in Western Victoria

Sloss,; De, Johnston

doi:10.1111/j.1751-0813.1967.tb04757.x

Cited by 20 publications

(1 citation statement)

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“…Schistosomus reflexus (SR) is the most form of common congenital anomaly found in cases of cattle dystocia; it occurs mainly in cattle, but is also common in other domesticated animals. The prevalence rate of this fatal congenital syndrome ranges from as low as 0.01% to as high as 1.3% of dystocia cases ( 1 , 2 ). SR occurs mainly in bovines and rarely in other species such as sheep, goats, pigs, dogs, cats, donkeys, and sea turtles ( Lepidochelys olivacea ) ( 3 – 8 ).…”

Section: Introductionmentioning

confidence: 99%

Case report: Investigation of genetic mutations in a case of schistosomus reflexus in a Holstein dairy cattle fetus in Korea

Park,

Chai,

Lim

et al. 2023

Front. Vet. Sci.

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Schistosomus reflexus (SR) is one of the most common congenital anomalies found in cases of cattle dystocia; this disorder occurs mostly in cattle. Congenital anomalies such as SR are caused by various genetic and environmental factors, but no specific cause has been elucidated for SR. This study reports a case of SR in a Holstein dairy cattle fetus with congenital anomalies in Korea. Grossly, a distinct spine curvature was observed between the thoracic and lumbar vertebrae, accompanied by a consequential malformation from the sacrum to the occipital bone. Furthermore, the thoracic and abdominal organs were exposed. In computed tomography (CT) images, mild and severe kyphoscoliosis was observed in T1~11 and L1~6, respectively. Additionally, vertebral dysplasia was observed in S1~5 and Cd 1~5. To pinpoint the causal genes and mutations, we leveraged a custom 50K Hanwoo SNP-Chip and the Online Mendelian Inheritance in Animals (OMIA) database. As a result, we identified a nonsense mutation in apoptotic protease activating factor 1 (APAF1) within HH1 that was associated with a decrease in conception rate and an increase in abortion in Holstein dairy cattle. The genotype of the SR case was A/A, and most of the 1,142 normal Holstein dairy cattle tested as a control group had the genotype G/G. In addition, the A/A genotype did not exist in the control group. Based on the pathological, genetic, and radiological findings, the congenital abnormalities observed were diagnosed as SR.

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Section: Introductionmentioning

confidence: 99%