To efficiently establish a finite element model that is highly compatible with the intricate microstructure of foam materials, this study carries out simulation and experimental investigations into open cell foams and explores their compression behavior assuming isotropy. Using an in-house algorithm, we optimize the traditional power diagram model, which is widely used in foam finite element simulation. Specifically, a parameterized geometric foam model is developed based on the centroidal and capacity constrained power diagram (CCCPD), which accurately reflects the internal meso-structure of foam materials. The optimized foam model can restore the typical deformation process of foams under compressive load, thus addressing the limitations of existing foam models. The accuracy of the optimized model is validated by conducting uniaxial Quasi-static compression experiments on foamed thermoplastic polyurethane (TPU) material and comparing the experimental results of the 3D printing model with the simulation results of the optimized model. The improved foam model serves as a basis for future research on open cell foam materials.