1999
DOI: 10.1046/j.1464-410x.1999.00954.x
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The cellular and molecular basis of prostate cancer

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Cited by 57 publications
(48 citation statements)
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“…The percentage of the stained cells was decided by calculating the average of the 10 fields. Tissues stained with less than 1% of cells were classified as negative stain or unstained (2). Those with up to 30% of the cells stained were classified as weakly positive stain (1).…”
Section: Immunocytochemical Detection Of Opn Protein In Prostate Tissuesmentioning
confidence: 99%
See 1 more Smart Citation
“…The percentage of the stained cells was decided by calculating the average of the 10 fields. Tissues stained with less than 1% of cells were classified as negative stain or unstained (2). Those with up to 30% of the cells stained were classified as weakly positive stain (1).…”
Section: Immunocytochemical Detection Of Opn Protein In Prostate Tissuesmentioning
confidence: 99%
“…The complicated genetic events responsible for tumorigenicity and metastasis of prostate cancer may be classified in a simple manner as the increased activity of the possible cancer-promoting genes (oncogenes) and the diminished activity of the possible cancer-suppressor genes (tumour suppressor genes). 2,3 Thus, identification of these oncogenes and tumour suppressor genes and determination of their potential significance in prognosis, diagnosis and treatment are of paramount importance in prostate cancer research.…”
mentioning
confidence: 99%
“…Human prostate cancer is the most commonly diagnosed malignancy among men and the second leading cause of cancer death in the US, most dying from metastatic disease (Foster et al, 1999). The major difficulty is the lack of effective mechanism-based treatment for the disease.…”
Section: Introductionmentioning
confidence: 99%
“…Prostate cancers are characterised by clinical and biological heterogeneity with complex molecular and epidemiological dimensions (1,2). At the time of diagnosis, patients may have already developed metastatic disease, although this may not be clinically apparent.…”
Section: Introductionmentioning
confidence: 99%