The cellular blood elements of normal kittens

Hammon, William D.

doi:10.1002/ar.1090760302

Cited by 8 publications

(2 citation statements)

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“…Chart 1 shows such a course in one kitten which died and in another which recovered. Studies made by us on the blood of normal kittens (2) show that under ordinary circumstances the number of lymphocytes in the circulation remains relatively constant, despite wide physiological fluctuations in the total leucocyte count, which are due almost entirely to changes in the number of circulating polymorphonuclear cells. Such marked reduction of the lymphocytes as occurs during the incubation period of this disease becomes more significant when considered in respect to this otherwise normal constancy.…”

Section: Effects On the Leucocytes And Leucopoietic Tissuesmentioning

confidence: 96%

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Further Studies on the Blood and the Hematopoietic Tissues in Malignant Panleucopenia of Cats

Hammon

Enders

1939

Journal of Experimental Medicine

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In a recent report (1) we described a highly fatal epizootic disease of cats which, we demonstrated, is caused by a filterable agent. The usual clinical course is characterized by a fulminating leucopenia associated with 1 or 2 days of manifest illness during which vomiting, moderate elevation of temperature and progressive anorexia and weakness are almost constant features. A large series of autopsies with tissue sections showed the constant, outstanding pathological changes restricted to the bone marrow, lymphoid tissues and intestines. In these affected organs eosinophilic intranuclear inclusion bodies were found to be a characteristic feature. We have more recently, through the observation and autopsy of approximately 50 more kittens suffering from this infection, noted several pathological changes, not previously described, related to the blood and the hematopoietic tissues. The description of these which forms the matter of this report is of value, we believe, in the interpretation of the causes underlying the observed quantitative abnormalities of the cellular elements of the blood.

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Section: Effects On the Leucocytes And Leucopoietic Tissuesmentioning

confidence: 96%

“…In normal kittens we found hemolysis of erythrocytes to begin at 0.58 to 0.60 per cent NaC1 and to be complete at from 0.46 to 0.48 per cent (2). The fragility range was tested on 3 experimentally infected animals at different times during the course of the disease and in one case during early recovery (see Table I).…”

Section: Effects On the Erythrocytesmentioning

confidence: 99%